Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

W518107

Sigma-Aldrich

Sucrose acetate isobutyrate

Synonym(s):

SAIB

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C40H62O19
Molecular Weight:
846.91
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
NACRES:
NA.21

biological source

synthetic

Quality Level

grade

Kosher

bp

288 °C

density

1.146 g/mL at 25 °C

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

Organoleptic

odorless

SMILES string

CC(C)C(=O)OC[C@]1(O[C@H](COC(C)=O)[C@@H](OC(=O)C(C)C)[C@@H]1OC(=O)C(C)C)O[C@H]2O[C@H](COC(C)=O)[C@@H](OC(=O)C(C)C)[C@H](OC(=O)C(C)C)[C@H]2OC(=O)C(C)C

InChI

1S/C40H62O19/c1-18(2)33(43)51-17-40(32(57-38(48)23(11)12)29(54-35(45)20(5)6)27(58-40)16-50-25(14)42)59-39-31(56-37(47)22(9)10)30(55-36(46)21(7)8)28(53-34(44)19(3)4)26(52-39)15-49-24(13)41/h18-23,26-32,39H,15-17H2,1-14H3/t26-,27-,28-,29-,30+,31-,32+,39-,40+/m1/s1

InChI key

ZNEBZIJCDDCNRC-SWTLDUCYSA-N

Related Categories

Application


  • An ultrasound-triggered injectable sodium alginate scaffold loaded with electrospun microspheres for on-demand drug delivery to accelerate bone defect regeneration.: This study highlights the use of Sucrose Acetate Isobutyrate (SAIB) in developing advanced drug delivery systems. SAIB is utilized to enhance the stability and controlled release properties of drug-loaded microspheres integrated into sodium alginate scaffolds, offering precise therapeutic management in bone regeneration applications (Yi Y et al., 2024).

  • Sustained Release of Dexamethasone from 3D-Printed Scaffolds Modulates Macrophage Activation and Enhances Osteogenic Differentiation.: Incorporating SAIB into 3D-printed scaffolds has shown to effectively control the release rates of dexamethasone, a therapeutic agent, facilitating improved osteogenic differentiation and reduced inflammatory responses, crucial for bone healing and regeneration (Majrashi M et al., 2023).

  • Application of Sucrose Acetate Isobutyrate in Development of Co-Amorphous Formulations of Tacrolimus for Bioavailability Enhancement.: Research demonstrates how SAIB can be used to develop co-amorphous drug formulations, specifically for tacrolimus, to enhance its bioavailability. This approach addresses significant challenges in drug solubility and stability, marking a significant advance in the formulation of poorly water-soluble drugs (Mohamed EM et al., 2023).

Disclaimer

For R&D or non-EU Food use. Not for retail sale.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Rasmus I Jølck et al.
Advanced healthcare materials, 3(10), 1680-1687 (2014-04-16)
External beam radiation therapy relies on the ability to deliver high radiation doses to tumor cells with minimal exposure to surrounding healthy tissue. Advanced irradiation techniques, including image-guided radiation therapy (IGRT), rely on the ability to locate tumors to optimize
Jianbo Guo et al.
AAPS PharmSciTech, 16(4), 973-985 (2015-01-23)
Our previous studies revealed that the PLGA-based particulate systems loaded with cucurbitacin showed limited anti-melanoma efficiency in xenograft animal models after intratumoral injection, which was due to the undesirable initial burst release and the leakage of the particulate carriers from

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service