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Merck
CN

W384704

L-Lysine

≥97%

Synonym(s):

(S)-2,6-Diaminocaproic acid

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About This Item

Linear Formula:
H2N(CH2)4CH(NH2)CO2H
CAS Number:
56-87-1
Molecular Weight:
146.19
PubChem Substance ID:
24901905
eCl@ss:
32160406
UNSPSC Code:
12164502
FEMA Number:
3847
Flavis number:
17.026
EC Number:
200-294-2
MDL number:
MFCD00064433
Beilstein/REAXYS Number:
1722531

Key Documents

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SMILES string

NCCCC[C@H](N)C(O)=O

InChI key

KDXKERNSBIXSRK-YFKPBYRVSA-N

InChI

1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/t5-/m0/s1

biological source

synthetic

assay

≥97%

optical activity

[α]20/D +24°, c = 2 in 0.6 M HCl

mp

215 °C (dec.) (lit.)

solubility

H2O: 10%, clear, colorless to light greenish-yellow, H2O: 10%, clear, colorless to yellow

cation traces

As: ≤3 ppm, Cd: ≤1 ppm, Hg: ≤1.0 ppm, Pb: ≤10 ppm

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

odorless

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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
STBF9741V
MKBX0765V
MKBK5044V
STBF6195V
MKBV2059V

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Sofia Faraasen et al.
Pharmaceutical research, 20(2), 237-246 (2003-03-15)
The purpose of this study was to demonstrate specific receptor-mediated targeting of phagocytes by functional surface coatings of microparticles, shielding from nonspecific phagocytosis and allowing ligand-specific interactions via molecular recognition. Coatings of the comb polymer poly(L-lysine)-g-poly(ethylene glycol) (PLL-g-PEG) were investigated
Valentina R Minciacchi et al.
Oncotarget, 6(13), 11327-11341 (2015-04-11)
Large oncosomes (LO) are atypically large (1-10 µm diameter) cancer-derived extracellular vesicles (EVs), originating from the shedding of membrane blebs and associated with advanced disease. We report that 25% of the proteins, identified by a quantitative proteomics analysis, are differentially
Lubin Jiang et al.
Nature, 499(7457), 223-227 (2013-07-05)
The variant antigen Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1), which is expressed on the surface of P. falciparum-infected red blood cells, is a critical virulence factor for malaria. Each parasite has 60 antigenically distinct var genes that each code
Amélie Fradet-Turcotte et al.
Nature, 499(7456), 50-54 (2013-06-14)
53BP1 (also called TP53BP1) is a chromatin-associated factor that promotes immunoglobulin class switching and DNA double-strand-break (DSB) repair by non-homologous end joining. To accomplish its function in DNA repair, 53BP1 accumulates at DSB sites downstream of the RNF168 ubiquitin ligase.
Scott R Floyd et al.
Nature, 498(7453), 246-250 (2013-06-04)
DNA damage activates a signalling network that blocks cell-cycle progression, recruits DNA repair factors and/or triggers senescence or programmed cell death. Alterations in chromatin structure are implicated in the initiation and propagation of the DNA damage response. Here we further
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