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W291501

Sigma-Aldrich

Polysorbate 20

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Synonym(s):
Cremophor PS 20, Monebatt - 20
CAS Number:
9005-64-5
FEMA Number:
2915
MDL number:
MFCD00165986
UNSPSC Code:
12164502
NACRES:
NA.21

reg. compliance

FDA 21 CFR 172.515
FDA 21 CFR 173.310
FDA 21 CFR 175.105
FDA 21 CFR 178.3400

Quality Level

400

description

Biological source: corn or palm

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

no known allergens

Organoleptic

alcohol

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

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General description

Polysorbate 20 is a hydrophilic nonionic surfactant generally used as emulsifiers, dispersing agent and solubilizer.

Application

Polysorbate 20 has been used in a study to assess its potential as a generally recognized as safe (GRAS) plasticizer in imparting plasticity to carnauba wax.

Disclaimer

For R&D or non-EU Food use. Not for retail sale.

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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CRC Handbook of Food, Drug, and Cosmetic Excipients, 295-296 (1992)
Plasticisation of carnauba wax with generally recognised as safe (GRAS) additives.
Zhang Y, et al.
Polymer, 86, 208-219 (2016)
Julie Beegle et al.
Stem cells (Dayton, Ohio), 33(6), 1818-1828 (2015-02-24)
Mesenchymal stem cells/multipotent stromal cells (MSCs) are promising therapeutics for a variety of conditions. However, after transplantation, cell retention remains extremely challenging. Given that many hypoxic signals are transitory and that the therapeutic administration of MSCs is typically into tissues
Daniel C Zielinski et al.
Nature communications, 6, 7101-7101 (2015-06-10)
Drug side effects cause a significant clinical and economic burden. However, mechanisms of drug action underlying side effect pathogenesis remain largely unknown. Here, we integrate pharmacogenomic and clinical data with a human metabolic network and find that non-pharmacokinetic metabolic pathways

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