Skip to Content
Merck
CN
All Photos(1)

Documents

W255505

Sigma-Aldrich

ω-6-Hexadecenlactone

≥98%

Synonym(s):

ambrettolide

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C16H28O2
CAS Number:
Molecular Weight:
252.39
FEMA Number:
2555
EC Number:
Council of Europe no.:
180
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
10.003
NACRES:
NA.21

biological source

synthetic

Quality Level

Agency

meets purity specifications of JECFA

reg. compliance

FDA 21 CFR 117
FDA 21 CFR 172.515

Assay

≥98%

refractive index

n20/D 1.479 (lit.)

bp

185-190 °C/16 mmHg (lit.)

density

0.956 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

Organoleptic

soapy; sweet

SMILES string

O=C1CCCC\C=C\CCCCCCCCCO1

InChI

1S/C16H28O2/c17-16-14-12-10-8-6-4-2-1-3-5-7-9-11-13-15-18-16/h4,6H,1-3,5,7-15H2/b6-4+

InChI key

HMWPDRYGIBLSHB-GQCTYLIASA-N

Related Categories

General description

ω-6-Hexadecenlactone is a macrocyclic lactone generally used as a fragrance ingredient due to its musk-like odor. It occurs naturally in ambrette seeds (Abelmoschus moschatus).

Application


  • RIFM fragrance ingredient safety assessment, ψ-6-hexadecenlactone, CAS Registry Number 7779-50-2.: This study conducted a comprehensive safety assessment of ψ-6-hexadecenlactone as a fragrance ingredient. The research concluded that this compound is safe for use in fragrance products under the conditions evaluated (Api et al., 2024).

  • Simple magnesium alkoxides: synthesis, molecular structure, and catalytic behaviour in the ring-opening polymerization of lactide and macrolactones and in the copolymerization of maleic anhydride and propylene oxide.: This study explored the synthesis and catalytic behavior of magnesium alkoxides, including their efficacy in ring-opening polymerization of macrolactones like ψ-6-hexadecenlactone. The findings highlight their potential in producing biodegradable polymers (Wannipurage et al., 2023).

  • One-Pot Terpolymerization of Macrolactones with Limonene Oxide and Phtalic Anhydride to Produce di-Block Semi-Aromatic Polyesters.: This research demonstrated a novel method for the terpolymerization of macrolactones, including ψ-6-hexadecenlactone, to create innovative semi-aromatic polyesters with potential applications in advanced material science (D′Auria et al., 2022).

  • Fragrance material review on ψ-6-hexadecenlactone.: This review summarized the existing data on ψ-6-hexadecenlactone, focusing on its use in fragrance products and providing a detailed analysis of its safety and efficacy as a fragrance ingredient (McGinty et al., 2011).

Disclaimer

For R&D or non-EU Food use. Not for retail sale.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

WGK

WGK 2

Flash Point(F)

235.4 °F

Flash Point(C)

113 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Fragrance material review on ?-6-hexadecenlactone.
McGinty D, et al.
Food And Chemical Toxicology, 49, S207-S211 (2011)
A toxicological and dermatological assessment of macrocyclic lactone and lactide derivatives when used as fragrance ingredients.
Belsito D, et al.
Food And Chemical Toxicology, 49, S219-S241 (2011)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service