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W224707

Sigma-Aldrich

L-Carveol, mixture of cis and trans

≥95%, FG

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Synonym(s):
(−)-Carveol, mixture of isomers, p-Mentha-6,8-dien-2-ol
Empirical Formula (Hill Notation):
C10H16O
CAS Number:
Molecular Weight:
152.23
FEMA Number:
2247
EC Number:
Council of Europe no.:
2027
MDL number:
UNSPSC Code:
12164502
PubChem Substance ID:
Flavis number:
2.062
NACRES:
NA.21

biological source

synthetic

Quality Level

grade

FG
Fragrance grade
Halal
Kosher

Agency

follows IFRA guidelines

reg. compliance

EU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
FDA 21 CFR 117
FDA 21 CFR 172.515

Assay

≥95%

optical activity

[α]22/D −115°, c = 1 in chloroform

composition

contains IFRA restricted Carvone

refractive index

n20/D 1.496 (lit.)

bp

226-227 °C/751 mmHg (lit.)

density

0.958 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

no known allergens

fragrance allergen

carvone

Organoleptic

minty; herbaceous

SMILES string

CC(=C)[C@@H]1CC=C(C)C(O)C1

InChI

1S/C10H16O/c1-7(2)9-5-4-8(3)10(11)6-9/h4,9-11H,1,5-6H2,2-3H3/t9-,10?/m1/s1

InChI key

BAVONGHXFVOKBV-YHMJZVADSA-N

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General description

L-Carveol, mixture of cis and trans is a cyclic terpene alcohol that can be used as a flavoring agent and fragrance ingredient.{80

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 2

Flash Point(F)

208.4 °F

Flash Point(C)

98 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Jenna L E Morrish et al.
Biotechnology letters, 30(7), 1245-1250 (2008-03-11)
The aqueous substrate and product toxicity thresholds in the microbial biotransformation of (-)-trans-carveol to the fragrance/flavor compound (R)-(-)-carvone by Rhodococcus erythropolis were determined. Above aqueous phase concentrations of approx. 500 mg carveol/l and 200-600 mg carvone/l, the biotransformation activity of
Jenna L E Morrish et al.
Biotechnology and bioengineering, 101(4), 768-775 (2008-05-15)
The microbial biotransformation of (-)-trans-carveol to the flavor and fragrance compound (R)-(-)-carvone by Rhodococcus erythropolis DCL14 was carried out in a 3 L two phase partitioning bioreactor with an immiscible liquid second phase in an effort to improve upon the
Alison Li Lin et al.
Life sciences, 79(1), 21-29 (2006-01-27)
2,6-Diisopropylphenol (Propofol) is a short-acting intravenous anesthetic that is rapidly metabolized by glucuronidation and ring hydroxylation catalyzed by cytochrome P450. The goal of this research was to determine whether dietary monoterpene alcohols (MAs) could be used to prolong the anesthetic
W A Duetz et al.
Applied and environmental microbiology, 67(6), 2829-2832 (2001-05-26)
The toluene-degrading strain Rhodococcus opacus PWD4 was found to hydroxylate D-limonene exclusively in the 6-position, yielding enantiomerically pure (+) trans-carveol and traces of (+) carvone. This biotransformation was studied using cells cultivated in chemostat culture with toluene as a carbon
Aleem U Khand et al.
Journal of the American College of Cardiology, 42(11), 1944-1951 (2003-12-10)
This study examined the relative merits of digoxin, carvedilol, and their combination for the management of patients with atrial fibrillation (AF) and heart failure (HF). In patients with AF and HF, both digoxin and beta-blockers reduce the ventricular rate, and

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