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T70408

Sigma-Aldrich

3,4,5-Trimethoxycinnamic acid

97%

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About This Item

Linear Formula:
(CH3O)3C6H2CH=CHCO2H
CAS Number:
Molecular Weight:
238.24
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

Assay

97%

mp

125-127 °C (lit.)

SMILES string

COc1cc(\C=C\C(O)=O)cc(OC)c1OC

InChI

1S/C12H14O5/c1-15-9-6-8(4-5-11(13)14)7-10(16-2)12(9)17-3/h4-7H,1-3H3,(H,13,14)/b5-4+

InChI key

YTFVRYKNXDADBI-SNAWJCMRSA-N

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sarvesh Kumar et al.
Biochemistry, 44(48), 15944-15952 (2005-11-30)
We report here the isolation and characterization of two active principles, ethyl 3',4',5'-trimethoxycinnamate (1) and piperine (2), from the combined hexane and chloroform extracts of Piper longum. Using primary human umbilical vein endothelial cells, we evaluated the activities of compound
Zhenghang Zhao et al.
Biological & pharmaceutical bulletin, 36(2), 238-244 (2012-12-01)
3,4,5-Trimethoxycinnamic acid (TMCA), methyl 3,4,5-trimethoxycinnamate (M-TMCA) and p-methoxycinnamic acid (PMCA) have been identified as the major bioactive components in the serum collected from rats treated with oral administration of Polygalae Radix ("YuanZhi," the roots of Polygala tenuifolia WILLD.), a traditional
Yingming Wu et al.
Organic letters, 11(3), 597-600 (2008-12-25)
A highly flexible and concise total synthesis of (+)-podophyllotoxin featured with an enantioselective sequential conjugate addition-allylation reaction was reported. Starting from commercially available 3,4,5-trimethoxycinnamic acid, this new route leads to (+)-podophyllotoxin 1 in only eight steps with 29% overall yield.
[The detection of Azotobacter and its significance in criminal technical soil examinations].
E Kissling
Archiv fur Kriminologie, 165(1-2), 27-34 (1980-01-01)
Jae-Chul Jung et al.
Chemical biology & drug design, 81(3), 389-398 (2012-11-06)
A series of 3,4,5-trimethoxycinnamic acid derivatives was prepared and evaluated for antinarcotic effects on morphine dependence in mice and binding affinities on serotonergic receptors. The key synthetic strategies involve generation of ketones 6-7, esters 9-12 through condensation reaction, and amides

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