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QBD10931

Sigma-Aldrich

m-dPEG®36-MAL

>95% (HPLC)

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Synonym(s):
mPEG36-MAL, mPEG-maleimide, mPEG1500-maleimide, mPEG36-maleimide
Empirical Formula (Hill Notation):
C80H154N2O39
Molecular Weight:
1768.07
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.22

Assay

>95% (HPLC)

form

solid or viscous liquid

reaction suitability

reaction type: Pegylations

polymer architecture

shape: linear
functionality: monofunctional

shipped in

ambient

storage temp.

−20°C

Features and Benefits

m-dPEG36-MAL is a methyl-terminated, thiol-reactive, monodispersed PEGylation product designed for surface and biomolecule modification. This single molecular weight PEG reagent has a discrete chain length of 116 atoms spanning a distance of 132.4 Å. One end of the molecule terminates in a maleimido-propionic acid group, which is conjugated to the dPEG spacer by an amide bond. The maleimide moiety reacts with sulfhydryls to form a thioether bond. dPEG36 is a monodisperse equivalent of the polymeric PEG1500. Modification of cysteine residues on peptides, proteins, and other sulfhydryl-containing molecules with m-dPEG36-MAL will increase hydrophilicity and decrease immunogenicity.

Legal Information

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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