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QBD10289

Sigma-Aldrich

m-dPEG®12-MAL

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Synonym(s):
Polyethylene glycol
Empirical Formula (Hill Notation):
C32H58N2O15
CAS Number:
88504-24-9
Molecular Weight:
710.81
MDL number:
MFCD11041152
UNSPSC Code:
51171641
PubChem Substance ID:
329823909
NACRES:
NA.22

Assay

>90%

form

solid or viscous liquid

reaction suitability

reagent type: chemical modification reagent
reagent type: cross-linking reagent
reactivity: sulfhydryl reactive
reagent type: linker
reactivity: thiol reactive

polymer architecture

shape: linear
functionality: monofunctional

shipped in

ambient

storage temp.

−20°C

SMILES string

COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O

Related Categories

Features and Benefits

The m-dPEG®12-MAL provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG®12-MAL reacts with free sulfhydryls in a rapid, highly specific reaction in aqueous media at pH 6.5-7.5.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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