QBD10127
Acid-dPEG®13-NHS ester
Synonym(s):
Polyethylene glycol
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About This Item
Empirical Formula (Hill Notation):
C34H61NO19
Molecular Weight:
787.84
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.22
Assay
>90%
form
solid or viscous liquid
reaction suitability
reagent type: cross-linking reagent
reactivity: amine reactive
polymer architecture
shape: linear
functionality: heterobifunctional
shipped in
ambient
storage temp.
−20°C
SMILES string
O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)ON1C(CCC1=O)=O
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Features and Benefits
Acid-dPEG®13-NHS ester, a unique heterobifunctional dPEG® crosslinking product, allows conjugation to two different moieties, each containing free amines. Because the single molecular weight dPEG® spacers contain an N-hydroxysuccinimide ester only on one end of the spacer, greater control of the conjugation reaction can be maintained. The free acid end of the spacer can be left unreacted to modify the surface properties of the molecule to which it is conjugated, or the free acid end can be activated and conjugated to a different group at a later time. The dPEG® spacers provide precise spacing/distance control, and the dPEG® itself provides the well-known benefits of increased water solubility; decreased immunogenicity; protection from proteolysis; increased hydrodynamic volume; and increased serum half-life.
Legal Information
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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