P56003
Pyrazine
≥99%
Synonym(s):
1,4-Diazabenzene, 1,4-Diazine, Paradiazine, Piazine, p-Diazine
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About This Item
Quality Level
Assay
≥99%
form
crystals
bp
115-116 °C (lit.)
mp
50-56 °C (lit.)
density
1.031 g/mL at 25 °C (lit.)
SMILES string
c1cnccn1
InChI
1S/C4H4N2/c1-2-6-4-3-5-1/h1-4H
InChI key
KYQCOXFCLRTKLS-UHFFFAOYSA-N
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General description
Pyrazine is a 1,4-diazine and an electron-deficient N-heteroarene found in several natural products, APIs, agrochemicals, and functional materials.
Application
Pyrazine can be used:
- As a bridging ligand in the synthesis of Cu(II) linear chain coordination complexes.
- To prepare Cu(I) derived coordination polymers, which are used in the synthesis of metal-organic frameworks (MOFs).
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Flam. Sol. 1
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Pyrazine-bridged Cu (ii) chains: diaquabis (n-methyl-2-pyridone) copper (ii) perchlorate complexes
Dalton Transactions, 49(39), 13693-13703 (2020)
Microwave assisted hydrothermal synthesis of a novel CuI-sulfate-pyrazine MOF
Inorganic Chemistry Communications, 10(8), 921-924 (2007)
Direct C-H photoarylation of diazines using aryldiazonium salts and visible-light
Royal Society of Chemistry Advances, 10(52), 31115-31122 (2020)
Organic letters, 16(3), 864-867 (2014-01-15)
A one-step transformation of heterocyclic N-oxides to 2-alkyl-, aryl-, and alkenyl-substituted N-heterocycles is described. The success of this broad-scope methodology hinges on the combination of copper catalysis and activation by lithium fluoride or magnesium chloride. The utility of this method
Journal of food science, 80(10), C2140-C2146 (2015-09-27)
Rosmarinic acid and Epigallocatechin gallate concentrations were studied as natural inhibitors of Maillard browning in glucose/glycine model systems, and in bakery rolls and applesauce. The concentrations of the inhibitors were varied to determine the highest level of inhibition without a
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