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P40506

Sigma-Aldrich

N-Phthaloylglycine

97%

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Synonym(s):
1,3-Dioxo-2-isoindolineacetic acid, Phthalimidoacetic acid
Empirical Formula (Hill Notation):
C10H7NO4
CAS Number:
4702-13-0
Molecular Weight:
205.17
Beilstein:
184174
EC Number:
225-177-3
MDL number:
MFCD00005900
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24898488
NACRES:
NA.22

Quality Level

100

Assay

97%

form

powder or crystals

reaction suitability

reaction type: solution phase peptide synthesis

color

white

mp

193-196 °C (lit.)

SMILES string

OC(=O)CN1C(=O)c2ccccc2C1=O

InChI

1S/C10H7NO4/c12-8(13)5-11-9(14)6-3-1-2-4-7(6)10(11)15/h1-4H,5H2,(H,12,13)

InChI key

WQINSVOOIJDOLJ-UHFFFAOYSA-N

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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O abu Salach et al.
Pharmaceutical research, 11(10), 1429-1434 (1994-10-01)
Glycine, in addition to GABA, is one of the most important neurotransmitter amino acids. The described structure pharmacokinetic pharmacodynamic relationships (SPPR) study explored the possibility of utilizing phthaloyl derivatives of glycine as new antiepileptics. This was carried out by investigating
Nasima Arshad et al.
Journal of photochemistry and photobiology. B, Biology, 117, 228-239 (2012-11-20)
Ni(II), Cu(II) and Zn(II) metal complexes of N-phthaloylglycine were synthesized, characterized, reported for single crystal X-ray diffraction analysis for Ni(II) complex, and investigated for their binding with DNA under physiological conditions, using spectroscopic (UV-visible and fluorescence) and hydrodynamic techniques. Experimental
Julija Matijević-Sosa et al.
Acta pharmaceutica (Zagreb, Croatia), 58(2), 231-236 (2008-06-03)
The aim of this study was to investigate the activity of N-phthaloyl-glycine-hydroxamic acid (Phth-Gly-HA) as a new iron chelator in vivo to be used in iron overload diseases. After intraperitoneal application of Phth-Gly-HA to male rats (1 mg kg(-1) body

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