Key Documents

View All Documentation

P39605

Phthalide

Name: Phthalide
Brand: ALDRICH

98%

Synonym(s):

1-Isobenzofuranone

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₈H₆O₂

CAS Number:

87-41-2

Molecular Weight:

134.13

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24898475

EC Number:

201-744-0

Beilstein/REAXYS Number:

114632

MDL number:

MFCD00005906

Assay:

98%

Form:

powder

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Quality Level

100

assay

98%

form

powder

bp

290 °C (lit.)

mp

71-74 °C (lit.)

SMILES string

O=C1OCc2ccccc12

InChI

1S/C8H6O2/c9-8-7-4-2-1-3-6(7)5-10-8/h1-4H,5H2

InChI key

WNZQDUSMALZDQF-UHFFFAOYSA-N

Description

Still not finding the right product?

Explore all of our products under Phthalide

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

305.6 °F - closed cup

flash_point_c

152 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Total synthesis of 7',8'-dihydroaigialospirol.

Tsz-Ying Yuen et al.

Organic letters, 14(19), 5154-5157 (2012-09-29)

A highly convergent total synthesis of 7',8'-dihydroaigialospirol is described. Key steps of the synthesis include a Nozaki-Hiyama-Kishi (NHK) coupling of an iodoalkyne with an advanced phthalide-aldehyde and a remarkable one-pot acid-mediated global deprotection/spiroacetalization.

Highly stereoselective chemoenzymatic synthesis of the 3H-isobenzofuran skeleton. Access to enantiopure 3-methylphthalides.

Juan Mangas-Sánchez et al.

Organic letters, 14(6), 1444-1447 (2012-03-08)

A straightforward synthesis of (S)-3-methylphthalides has been developed, with the key asymmetric step being the bioreduction of 2-acetylbenzonitriles. Enzymatic processes have been found to be highly dependent on the pH value, with acidic conditions being required to avoid undesired side

Palladium-catalyzed cascade aryl addition/intramolecular lactonization of phthalaldehyde to access 3-aryl- and alkenylphthalides.

Zhishi Ye et al.

The Journal of organic chemistry, 75(17), 6043-6045 (2010-08-28)

A palladium-catalyzed addition of arylboronic acids to phthalaldehyde, followed by an intramolecular lactonization to access 3-substituted phthalides, is described. The procedure tolerates a series of functional groups, such as methoxyl, fluoro, chloro, and trifluoromethyl groups. It represents a procedure for

View All Related Papers

Global Trade Item Number

SKU	GTIN
P39605-500G	04061834373353
P39605-100G	04061834373346