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P1659

Pelargonidin chloride

Name: Pelargonidin chloride
Brand: ALDRICH

Synonym(s):

3,4′,5,7-Tetrahydroxyflavylium chloride, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-1-benzopyrylium chloride, Pelargonidol chloride

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₁₁ClO₅

CAS Number:

134-04-3

Molecular Weight:

306.70

Beilstein:

3922945

EC Number:

205-127-7

MDL number:

MFCD00017589

UNSPSC Code:

12352100

PubChem Substance ID:

57654503

NACRES:

NA.22

form

powder

Quality Level

200

storage temp.

2-8°C

SMILES string

[Cl-].Oc1ccc(cc1)-c2[o+]c3cc(O)cc(O)c3cc2O

InChI

1S/C15H10O5.ClH/c16-9-3-1-8(2-4-9)15-13(19)7-11-12(18)5-10(17)6-14(11)20-15;/h1-7H,(H3-,16,17,18,19);1H

InChI key

YPVZJXMTXCOTJN-UHFFFAOYSA-N

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Related Categories

Heterocyclic Building Blocks

Application

Involved in pharmacological studies investigating the use of flavonoids as inhibitors of CD38

Antioxidant and anthocyanidin:

Found in various natural sources evaluated for inhibitory effects on colon and liver cancer cells
Used as hyroperoxide and hydrogen peroxide scavenging substance
Used to study relationship between structure, antioxidant capacity and redox potentials
Studied to determine the mechanism of radical-scavenging

Biochem/physiol Actions

Antioxidant and anthocyanidin.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Strawberry anthocyanins are recovered in urine as glucuro- and sulfoconjugates in humans.

Catherine Felgines et al.

The Journal of nutrition, 133(5), 1296-1301 (2003-05-06)

Anthocyanins are phenolic compounds widely distributed in fruits and vegetables. Their consumption has been shown to prevent some chronic diseases. Anthocyanin metabolism, however, is still not fully understood. The aim of this work was to evaluate the bioavailability of anthocyanins

Luteolin Shifts Oxaliplatin-Induced Cell Cycle Arrest at G₀/G₁ to Apoptosis in HCT116 Human Colorectal Carcinoma Cells.

Chan Ho Jang et al.

Nutrients, 11(4) (2019-04-17)

Certain antioxidative flavonoids are known to activate nuclear factor E2-related factor 2 (Nrf2), a transcription factor that regulates cellular antioxidants and detoxifying response and is reportedly highly activated in many types of cancers. Few studies on the potential undesired effects

Flavonoid glycosides are not transported by the human Na+/glucose transporter when expressed in Xenopus laevis oocytes, but effectively inhibit electrogenic glucose uptake.

Gabor Kottra et al.

The Journal of pharmacology and experimental therapeutics, 322(2), 829-835 (2007-05-15)

There is controversy as to whether intestinal absorption of glycosylated flavonoids, and particularly quercetin glycosides, involves their uptake in intact form via the human sodium-coupled glucose transporter hSGLT1. We here describe studies using Xenopus oocytes that express hSGLT1 and the

Impact of Anthocyanidins on Mitoxantrone-Induced Cytotoxicity and Genotoxicity: An In Vitro and In Vivo Analysis.

Sridaran Dhivya et al.

Integrative cancer therapies, 15(4), 525-534 (2016-05-06)

Hypothesis Anthocyanins possess well-known biological effects and suppress DNA damage induced by therapeutic topoisomerase poisons. Our study focusses on the modulatory effects of anthocyanidins-malvidin (MAL) and pelargonidin (PEL)-on topoisomerase II poison mitoxantrone (MXT)-induced cytotoxicity and genotoxicity in in vitro and

Noelia Castillo-Muñoz et al.

Journal of agricultural and food chemistry, 57(17), 7883-7891 (2009-08-14)

Garnacha Tintorera (also known as Alicante Bouschet) is one of the few V. vinifera grape cultivars with red-colored berry flesh. The study of the phenolic composition of both berry flesh and skin of Garnacha Tintorera grapes shows interesting findings. Anthocyanins

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