O3132
Oxibendazole
~98%
Synonym(s):
Methyl (5-propoxy-1H-benzimidazol-2-yl)carbamate
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About This Item
Empirical Formula (Hill Notation):
C12H15N3O3
CAS Number:
Molecular Weight:
249.27
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
243-877-7
MDL number:
Assay:
~98%
InChI key
RAOCRURYZCVHMG-UHFFFAOYSA-N
InChI
1S/C12H15N3O3/c1-3-6-18-8-4-5-9-10(7-8)14-11(13-9)15-12(16)17-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)
SMILES string
CCCOc1ccc2[nH]c(NC(=O)OC)nc2c1
assay
~98%
storage temp.
2-8°C
Quality Level
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Related Categories
Biochem/physiol Actions
Anthelminthic
Storage Class
11 - Combustible Solids
wgk
WGK 3
Regulatory Information
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G W Lubega et al.
Biochemical pharmacology, 41(1), 93-101 (1991-01-01)
The low- and high-affinity binding of tritiated benzimidazole anthelmintics (mebendazole and oxibendazole) to tubulin-containing supernatants derived from unembryonated eggs, third stage larvae or adult worms of thiabendazole-susceptible and -resistant strains of Haemonchus contortus were examined and compared. The displacement of
C Gokbulut et al.
Research in veterinary science, 72(1), 11-15 (2002-05-11)
Oxibendazole (OBZ) was administered to eight horses at an oral dose of 10 mg kg(-1) bodyweight each. Parent OBZ could only be detected in plasma at the 0.5 and 1.0 hours post administration sampling times and the mean maximum plasma
A field evaluation of three methods of administration of anthelminthics to horses.
C Uhlinger et al.
Equine veterinary journal, 24(6), 487-488 (1992-11-01)
S C Tolliver et al.
American journal of veterinary research, 54(6), 908-913 (1993-06-01)
Critical tests were conducted in horses (n = 11) with naturally acquired infections of benzimidazole (BZ)-resistant population-B small strongyles in 1989 and 1990. Anthelmintics administered were thiabendazole (44 mg/kg of body weight, n = 4), oxibendazole (10 mg/kg, n =
C Uhlinger et al.
Journal of the American Veterinary Medical Association, 201(1), 51-55 (1992-07-01)
Anthelmintic schedules that alternate between drug classes are widely used in horses. However, the results of investigations in which ovine nematode parasites were used have established that alternation of drug classes does not delay the development of drug resistance. This
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