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Merck
CN

M68423

N-Methyl-phenethylamine

99%

Synonym(s):

N-Methyl-2-phenylethylamine

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About This Item

Linear Formula:
C6H5CH2CH2NHCH3
CAS Number:
Molecular Weight:
135.21
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
209-632-3
Beilstein/REAXYS Number:
636347
MDL number:
Assay:
99%
Form:
liquid
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InChI

1S/C9H13N/c1-10-8-7-9-5-3-2-4-6-9/h2-6,10H,7-8H2,1H3

InChI key

SASNBVQSOZSTPD-UHFFFAOYSA-N

SMILES string

CNCCc1ccccc1

assay

99%

form

liquid

Quality Level

bp

203 °C (lit.)

density

0.93 g/mL at 25 °C (lit.)

Application

N-Methyl-phenethylamine can be used as a reactant:
  • To synthesize N-methyl-phenethylamine based tertiary amines by reacting with different alkyl halides in the presence of triphenylphosphine (TPP) and diisopropylazocarboxylate (DIAD) via N-alkylation reaction.
  • To fabricate photochemically stable, super-sensitive, and highly selective fluorescent film for the detection of N-methamphetamine (an illicit drug).
  • To prepare biologically active squaric acid N-hydroxylamide amide derivatives.

pictograms

CorrosionExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1

Storage Class

10 - Combustible liquids

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

监管及禁止进口产品
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Efficient synthesis of tertiary amines from secondary amines
Michio K, et al.
Tetrahedron Letters, 47, 4871-4875 (2006)
Fabrication of a new fluorescent film and its superior sensing performance to N-methamphetamine in vapor phase
H Meixia, et al.
Sensors and Actuators B, Chemical, 227 (2016)
Xulin Tan et al.
Journal of separation science, 30(12), 1888-1892 (2007-07-20)
A novel chiral stationary phase (CSP) for HPLC was prepared by bonding (R)-1-phenyl-2-(4-methylphenyl)ethylamine amide derivative of (S)-valine to aminopropyl silica gel through a 2-amino-3,5-dinitro-1-carboxamido-benzene unit. The CSP was used for the separation of some amino acid derivatives and pyrethroid insecticides
D Reid et al.
Pharmacology, biochemistry, and behavior, 24(6), 1547-1553 (1986-06-01)
The discriminative stimulus (cue) properties of phenylethylamine (PEA) were analysed in rodents in a conventional two lever FR10 operant drug discrimination task. Rats trained to discriminate phenylethylamine at 30 mg/kg showed complete dose-related generalization to PEA and to two potential
Aron D Mosnaim et al.
Neurochemical research, 38(4), 842-846 (2013-02-08)
Phenylethylamine and its monomethylated derivatives p-methylphenylethylamine, α-methylphenylethylamine, phenylethylamine itself, N-methylphenylethylamine, o-methylphenylethylamine, and β-methylphenylethylamine, readily cross the blood-brain barrier showing a brain-uptake index (%) ± SD (water considered 100 %), of 108 ± 11, 98 ± 14, 83 ± 6, 78

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