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Key Documents

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M5801

Sigma-Aldrich

3-Mercaptopropionic acid

≥99%

Synonym(s):

3-sulfanylpropanoic acid

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CN¥530.13
100 G
CN¥557.93
500 G
CN¥860.08

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Estimated to ship onJune 17, 2025Details

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5 G
CN¥530.13
100 G
CN¥557.93
500 G
CN¥860.08

About This Item

Linear Formula:
HSCH2CH2CO2H
CAS Number:
107-96-0
Molecular Weight:
106.14
Beilstein:
773807
EC Number:
203-537-0
MDL number:
MFCD00004897
UNSPSC Code:
12352103
PubChem Substance ID:
24897049
NACRES:
NA.23

CN¥530.13

Estimated to ship onJune 17, 2025Details

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vapor pressure

0.04 mmHg ( 20 °C)

Assay

≥99%

form

liquid

autoignition temp.

662 °F

refractive index

n20/D 1.492 (lit.)

bp

110-111 °C/15 mmHg (lit.)

mp

15-18 °C (lit.)

density

1.218 g/mL at 25 °C (lit.)

SMILES string

OC(=O)CCS

InChI

1S/C3H6O2S/c4-3(5)1-2-6/h6H,1-2H2,(H,4,5)

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Show Differences

1 of 4

This Item
6376880596716583
3-Mercaptopropionic acid ≥99%

M5801

3-Mercaptopropionic acid

3-Mercaptopropionic acid ≥99.0% (HPLC)

63768

3-Mercaptopropionic acid

3-Mercaptopropionic acid for synthesis

805967

3-Mercaptopropionic acid

2-Mercaptopropionic acid analytical standard

16583

2-Mercaptopropionic acid

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

100

form

liquid

form

liquid

form

liquid

form

-

density

1.218 g/mL at 25 °C (lit.)

density

1.218 g/mL at 25 °C (lit.)

density

1.22 g/cm3 at 20 °C

density

1.196 g/mL at 25 °C (lit.)

mp

15-18 °C (lit.)

mp

15-18 °C (lit.)

mp

17-19 °C

mp

10-14 °C (lit.)

vapor pressure

0.04 mmHg ( 20 °C)

vapor pressure

0.04 mmHg ( 20 °C)

vapor pressure

0.053 hPa ( 20 °C)

vapor pressure

-

General description

3-Mercaptopropionic acid (3-MPA) is used as a self-assembled monolayer (SAM) with a thiol and carboxylic groups. It has short carbon chains and is mainly used as a capping agent on a variety of nanoparticles.[1][2]

Application

3-MPA is used to produce hydrophilic SAMs, which are terminated with carboxylic acids and can be further functionalized[3] to introduce more complex end groups such as enzymes for biosensor applications.[4] SAMs of 3-MPA are capped on ZnSe quantum dots for the electrochemical detection of dopamine.[2] 3-MPA is used as a capping agent on CdTe quantum dot nanocrystals (QD NCs) for use as labeling materials in biomedical applications.[5][6] It can also be used to modify the surface of iron oxide nanoparticles (Fe2O3) in the extraction and preconcentration of Al3+ and Cr3+ ions from different biological samples.[7]

Pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

Signal Word

Danger

Hazard Statements

H290,H301,H314,H332

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Flash Point(F)

200.1 °F - closed cup

Flash Point(C)

93.4 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves
  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    STBL3616
    STBK9911
    STBK5458
    STBK2636
    STBJ8743

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    Pedrosa, V. A.; Caetano, J.; Machado, S. A. S.; Freire, R. S.; Bertotti, M.
    Electroanalysis, 19, 1415-1420 (2007)
    Studies on the adsorption of chromium (VI) onto 3-mercaptopropionic acid coated superparamagnetic iron oxide nanoparticles.
    Burks T, et al.
    Journal of Colloid and Interface Science, 425, 36-43 (2014)
    Coating aqueous quantum dots with silica via reverse microemulsion method: toward size-controllable and robust fluorescent nanoparticles.
    Yang Y, et al.
    Chemistry of Materials, 19(17), 4123-4128 (2007)
    Enhancement effect of illumination on the photoluminescence of water-soluble CdTe nanocrystals: Toward highly fluorescent CdTe/CdS core- shell structure.
    Bao H, et al.
    Chemistry of Materials, 16(20), 3853-3859 (2004)
    Atomic absorption spectrometric determination of Al3+ and Cr3+ after preconcentration and separation on 3-mercaptopropionic acid modified silica coated-Fe3O4 nanoparticles.
    Mashhadizadeh MH and Amoli-Diva M
    Journal of Analytical Atomic Spectrometry, 28(2), 251-258 (2013)
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