M4031
p-Menthane-1,8-diol monohydrate
Synonym(s):
cis-4-Hydroxy-α,α,4-trimethylcyclohexanemethanol monohydrate, cis-Terpin monohydrate, cis-p-Menthane-1,8-diol monohydrate
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About This Item
Empirical Formula (Hill Notation):
C10H20O2 · H2O
CAS Number:
Molecular Weight:
190.28
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
201-288-2
MDL number:
InChI key
JGKJMBOJWVAMIJ-OFAZAQPOSA-N
InChI
1S/C10H20O2.H2O/c1-9(2,11)8-4-6-10(3,12)7-5-8;/h8,11-12H,4-7H2,1-3H3;1H2/t8-,10+;
SMILES string
O.CC(C)(O)[C@@H]1CC[C@](C)(O)CC1
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Makiko Fujii et al.
Drug development and industrial pharmacy, 30(6), 673-677 (2004-08-03)
The enhancing effect of p-Menthane-3,8-diol (MDO) on skin permeation of antipyrine (ANP) and indomethacin (IM) through Yucatan micropig skin in vitro was compared with 1-menthol. p-Menthane-3,8-diol is a metabolite of 1-menthol and has little odor. It is easy to combine
Scott P Carroll et al.
Journal of the American Mosquito Control Association, 22(3), 507-514 (2006-10-28)
para-Menthane-3,8-diol(PMD) is a monoterpene spent product of the distillation of leaves of the Australian lemon-scented gum tree (updated nomenclature Corymbia citriodora ssp. citriodora). In April 2005, the U.S. Centers for Disease Control and Prevention (CDC) endorsed two non-deet mosquito repellents
Stephen S Barasa et al.
Journal of medical entomology, 39(5), 736-741 (2002-09-28)
Four stereoisomers of p-menthane-3,8-diol, which make up the natural product obtained from Eucalyptus citriodora, were synthesized through stereoselective procedures. Repellency assays showed that all the four were equally active against Anopheles gambiae s.s. Racemic blends and the diastereoisomeric mixture of
Donald R Barnard et al.
Journal of medical entomology, 39(6), 895-899 (2002-12-24)
IR3535, KBR3023, para-Menthane-3,8-diol (PMD), and deet were evaluated in controlled studies with human subjects (n = 5) for repellency to black salt marsh mosquitoes (Ochlerotatus taeniorhynchus Wiedemann), in the Everglades National Park, FL. In tests of 6-h duration, with an
J K Trigg
Journal of the American Mosquito Control Association, 12(2 Pt 1), 329-330 (1996-06-01)
A eucalyptus-based insect repellent (PMD) was evaluated against Culicoides impunctatus in Scotland in comparison with deet. In human landing catches, both repellents still afforded 98% protection from biting 8 h after application of 0.5 ml to the forearm. A second
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