Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

L091000

Sigma-Aldrich

N,N-Dimethylformamide

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
DMF, NSC 5356
Linear Formula:
HCON(CH3)2
CAS Number:
68-12-2
Molecular Weight:
73.09
Beilstein:
605365
EC Number:
200-679-5
MDL number:
MFCD00003284
UNSPSC Code:
12352200
PubChem Substance ID:
329817380
NACRES:
NA.51

vapor density

2.5 (vs air)

Quality Level

100

vapor pressure

2.7 mmHg ( 20 °C)

type

for DNA synthesis

product line

Proligo Reagents

form

liquid

autoignition temp.

833 °F

expl. lim.

15.2 %

storage condition

dry at room temperature

impurities

≤200 ppm water content (Karl Fischer)
≤9 ppm Amine content

color

clear

refractive index

n20/D 1.430 (lit.)

pH

6.7

bp

153 °C (lit.)

mp

−61 °C (lit.)

density

0.944 g/mL (lit.)

SMILES string

[H]C(=O)N(C)C

InChI

1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3

InChI key

ZMXDDKWLCZADIW-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

N,N-Dimethylformamide (DMF) is an amide that works as a multipurpose reagent that is an effective polar solvent for various compounds and a ligand for metallic compounds. It also acts as a key intermediate as an electrophilic or nucleophilic agent for mediating reactions as it delivers its own H, C, N, and O atoms in compound synthesis.

Application

DMF is a widely used polar solvent in which organic, organometallic, and bioorganic transformations are carried out. It is also a solvent for many hydrophobic organic compounds and acts as a source of building blocks in various organic synthesis reactions.
Solvent for many hydrophobic organic compounds.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B

WGK

WGK 2

Regulatory Information

新产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A Journey from June 2018 to October 2021 with N, N-Dimethylformamide and N, N-Dimethylacetamide as Reactants
Jacques Muzart
Molecules (Basel), 26(21) (2021)
Recent Uses of N, N-Dimethylformamide and N, N-Dimethylacetamide as Reagents
Jean Le Bras, Jacques Muzart
Molecules (Basel), 23(8) (2018)
N,N-Dimethylformamide: much more than a solvent
Jacques Muzart
Tetrahedron, 65, 8313?8323-8313?8323 (2009)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service