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Merck
CN

K3007

N-(β-Ketocaproyl)-L-homoserine lactone

≥98%, detection, for peptide synthesis

Synonym(s):

N-(3-Oxohexanoyl)-L-homoserine lactone

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About This Item

Empirical Formula (Hill Notation):
C10H15NO4
CAS Number:
Molecular Weight:
213.23
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22
MDL number:
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Product Name

N-(β-Ketocaproyl)-L-homoserine lactone, ≥98%

Quality Level

assay

≥98%

form

powder

color

white

application(s)

detection
peptide synthesis

storage temp.

−20°C

SMILES string

CCCC(=O)CC(=O)N[C@H]1CCOC1=O

InChI

1S/C10H15NO4/c1-2-3-7(12)6-9(13)11-8-4-5-15-10(8)14/h8H,2-6H2,1H3,(H,11,13)/t8-/m0/s1

InChI key

YRYOXRMDHALAFL-QMMMGPOBSA-N

General description

N-(β-Ketocaproyl)-L-homoserine lactone (3-oxo-C6-HSL) is one of the quorum signaling molecules for V. fischeri. 3-oxo-C6-HSL is produced by LuxI autoinducer synthase catalyzed reaction between S-adenosylmethionine and acylated-acyl carrier proteins (Acyl-ACPs). It can be used in analyzing the expression of the orthogonal specialized reporter genes.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Ling Yan et al.
Journal of microbiological methods, 68(1), 40-45 (2006-08-19)
The autoinducer N-(3-oxo-hexanoyl)-L-homoserine lactone (3-oxo-C6-HSL) plays a significant role in the quorum-sensing system of the marine bacterium Vibrio fischeri. Upon forming a transcriptional activation complex with LuxR, 3-oxo-C6-HSL induces transcription of the luxICDABEG operon, leading to the increased production of
John T Sexton et al.
Molecular systems biology, 16(7), e9618-e9618 (2020-07-17)
The engineering of advanced multicellular behaviors, such as the programmed growth of biofilms or tissues, requires cells to communicate multiple aspects of physiological information. Unfortunately, few cell-cell communication systems have been developed for synthetic biology. Here, we engineer a genetically
Xiaofei Qin et al.
Biomolecules, 8(3) (2018-09-06)
New approaches to deal with drug-resistant pathogenic bacteria are urgent. We studied the antibacterial effect of chitosans against an Escherichia coli quorum sensing biosensor reporter strain and selected a non-toxic chitosan to evaluate its quorum sensing (QS) inhibition activity and



Global Trade Item Number

SKUGTIN
K3007-50MG04061833868409
K3007-10MG04061832645049