JKA5101
HS-PEG7500-COOH
average MN 7,500, COOH, cross-linking reagent polymerization reactions thiol reactive, cross-linking reagent polymerization reactions amine reactive
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HS-PEG-COOH, Polyethylene glycol, Thiol-PEG-Carboxyl, HS-PEG-COOH
HS(CH2CH2O)nCH2COOH
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form
solid
mol wt
average Mn 7,500
reaction suitability
reagent type: cross-linking reagent
reaction type: Polymerization Reactions
reactivity: amine reactive
reagent type: cross-linking reagent
reaction type: Polymerization Reactions
reactivity: thiol reactive
polymer architecture
shape: linear
functionality: heterobifunctional
Related Categories
General description
Product is a thiolated carboxylic-polyethylene . 4α;-sulfanyl—ω carboxy PEG (HS–PEG–COOH) heterobifunctional PEGs with functional end-groups of very different reactivity. HS-PEG-COOH inhibits nonspecific binding to living cells.
Application
HS-PEG-COOH may be tethered to the gold nanoparticle end during the fabrication of epidermal growth factor (EGF)-conjugated surface-enhanced Raman spectroscopy (SERS) nanoparticles. HS-PEG-COOH was coated onto silicon-on-insulator photonic biosensor chips. Quantum dots (QD)/ virus-like particles (VLPs) could be obtained only from HS-PEG-COOH-coated QDs. It may be used to stabilize nanoparticles and prevent its aggregation.
Applications may include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization
Legal Information
Product of JenKem Technology
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Biosensors And Bioelectronics, 24(8), 2528-2533 (2009)
Antibody-functionalized SERS tags with improved sensitivity.
Chemical Communications (Cambridge, England), 47(31), 8784-8786 (2011)
Quantum dot encapsulation in viral capsids."
Nano Letters, 6(9), 1993-1999 (2006)
Biomaterials, 33(32) (2012)
Detection of circulating tumor cells in human peripheral blood using surface-enhanced Raman scattering nanoparticles.
Cancer Research, 71(5), 1526-1532 (2011)
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