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Safety Information

I6806

Sigma-Aldrich

Iodoacetic acid

98%

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About This Item

Linear Formula:
ICH2CO2H
CAS Number:
Molecular Weight:
185.95
Beilstein:
1739079
EC Number:
MDL number:
UNSPSC Code:
12352200

Assay

98%

mp

77-79 °C (lit.)

SMILES string

OC(=O)CI

InChI

1S/C2H3IO2/c3-1-2(4)5/h1H2,(H,4,5)

InChI key

JDNTWHVOXJZDSN-UHFFFAOYSA-N

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Application

Enolic radical and ketene precursor. SH modifier.
Reagent for the modification of cysteine residues in proteins.

replaced by

Product No.
Description
Pricing

Pictograms

Skull and crossbonesCorrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Eye Dam. 1 - Skin Corr. 1A

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Tetrahedron, 50, 7579-7579 (1994)
R Nemani et al.
Archives of biochemistry and biophysics, 300(1), 24-29 (1993-01-01)
Chemical modification of the sulfhydryl residues of the catalytic subunits of protein phosphatases 1 and 2A was studied. Both enzymes were inactivated by a variety of thiol group reagents. Mercurial compounds were the most effective inactivators. Of the alkylating agents
Tetrahedron, 49, 8465-8465 (1993)
T Sotelo-Hitschfeld et al.
Glia, 60(4), 674-680 (2012-02-01)
Neuronal activity is accompanied by a rapid increase in interstitial lactate, which is hypothesized to serve as a fuel for neurons and a signal for local vasodilation. Using FRET microscopy, we report here that the rate of glycolysis in cultured
X D Wang et al.
Journal of dental research, 92(10), 918-924 (2013-08-13)
Temporomandibular joint osteoarthritis (TMJOA) is clinically characterized by female preponderance, with a female-to-male ratio of more than 2:1; however, the underlying mechanism remains obscure. We examined the effects of estrogen on TMJOA induced by monosodium iodoacetate. Female rats were randomly

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