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Merck
CN

I27902

Isoprenaline hydrochloride

98%

Synonym(s):

(±)-Isoproterenol hydrochloride, 1-(3′,4′-Dihydroxyphenyl)-2-isopropylaminoethanol hydrochloride, N-Isopropyl-DL-noradrenaline hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C11H17NO3 · HCl
CAS Number:
51-30-9
Molecular Weight:
247.72
EC Number:
200-089-8
UNSPSC Code:
12352200
MDL number:
MFCD00012603
Beilstein/REAXYS Number:
3917363

Key Documents

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InChI

1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H

InChI key

IROWCYIEJAOFOW-UHFFFAOYSA-N

SMILES string

Cl.CC(C)NCC(O)c1ccc(O)c(O)c1

assay

98%

mp

165-175 °C (dec.) (lit.)

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Biochem/physiol Actions

β-adrenoceptor agonist; increases cytosolic cAMP.

Storage Class

13 - Non Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
055K1021
08604DH
07808PE
S29322
01723LC

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Aaron M Ring et al.
Nature, 502(7472), 575-579 (2013-09-24)
G-protein-coupled receptors (GPCRs) are integral membrane proteins that have an essential role in human physiology, yet the molecular processes through which they bind to their endogenous agonists and activate effector proteins remain poorly understood. So far, it has not been
M Morgan-Bathke et al.
Journal of dental research, 92(10), 911-917 (2013-07-26)
Autophagy is a catabolic pathway utilized to maintain a balance among the synthesis, degradation, and recycling of cellular components, thereby playing a role in cell growth, development, and homeostasis. Previous studies revealed that a conditional knockout of essential member(s) of
Michael Schwarzl et al.
Critical care medicine, 41(12), e401-e410 (2013-08-22)
We tested whether mild hypothermia impacts on circulatory and respiratory dysfunction during experimental endotoxemia. Randomized controlled prospective experimental study. Large animal facility, Medical University of Graz, Austria. Thirteen anesthetized and mechanically ventilated pigs. Lipopolysaccharide was administered for 4 hours. With
Jiao Li et al.
PloS one, 8(3), e58334-e58334 (2013-03-28)
Here we investigate how ß-adrenergic stimulation of the heart alters regulation of ryanodine receptors (RyRs) by intracellular Ca(2+) and Mg(2+) and the role of these changes in SR Ca(2+) release. RyRs were isolated from rat hearts, perfused in a Langendorff
Sachin Nayyar et al.
American journal of physiology. Heart and circulatory physiology, 305(8), H1181-H1188 (2013-08-13)
QT variability (QTV) signifies repolarization lability, and increased QTV is a risk predictor for sudden cardiac death. The aim of the present study was to investigate the role of autonomic nervous system activity on QTV. This study was performed in
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