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H43415

4-Hydroxy-6-methyl-2-pyrone

Name: 4-Hydroxy-6-methyl-2-pyrone
Brand: ALDRICH

98%

Synonym(s):

3,5-Dihydroxysorbic acid δ-lactone

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About This Item

Empirical Formula (Hill Notation):

C₆H₆O₃

CAS Number:

675-10-5

Molecular Weight:

126.11

Beilstein:

113815

EC Number:

211-619-2

MDL number:

MFCD00006641

UNSPSC Code:

12352100

PubChem Substance ID:

24895638

NACRES:

NA.22

Quality Level

100

Assay

98%

mp

188-190 °C (dec.) (lit.)

SMILES string

CC1=CC(O)=CC(=O)O1

InChI

1S/C6H6O3/c1-4-2-5(7)3-6(8)9-4/h2-3,7H,1H3

InChI key

NSYSSMYQPLSPOD-UHFFFAOYSA-N

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Related Categories

Organic Building Blocks

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Irreversible inactivation of chicken liver fatty acid synthetase by its substrates acetyl and malonyl CoA. Effect of temperature and NADP n fatty acid and triacetic acid lactone synthesis.

K R Srinivasan et al.

Biochemical and biophysical research communications, 99(3), 920-927 (1981-04-15)

Purification and properties of 6-methylsalicylic acid synthase from Penicillium patulum.

J B Spencer et al.

The Biochemical journal, 288 ( Pt 3), 839-846 (1992-12-15)

6-Methylsalicylic acid synthase has been isolated in homogeneous form from Penicillium patulum grown in liquid culture from a spore inoculum. The enzyme is highly susceptible to proteolytic degradation in vivo and in vitro, but may be stabilized during purification by

Rational pathway engineering of type I fatty acid synthase allows the biosynthesis of triacetic acid lactone from D-glucose in vivo.

Wenjuan Zha et al.

Journal of the American Chemical Society, 126(14), 4534-4535 (2004-04-09)

Metabolic pathway engineering is a powerful tool to synthesize structurally diverse and complex chemicals via genetic manipulation of multistep catalytic systems involved in cell metabolism. Here, we report the rational design of a fatty acid biosynthetic pathway, Brevibacterium ammoniagenes fatty

Microbial synthesis of triacetic acid lactone.

Dongming Xie et al.

Biotechnology and bioengineering, 93(4), 727-736 (2005-10-26)

Native g2ps1-encoded 2-pyrone synthase (2-PS) from Gerbera hybrida, a mutant Brevibacterium ammoniagenes fatty acid synthase B (FAS-B) and two different mutants of Penicillium patulum 6-methylsalycilic acid synthase (6-MSAS) are examined to identify the best enzyme to recruit for the microbial

Synthesis of acetoacetyl-CoA by bovine mammary fatty acid synthase.

S Ghayourmanesh et al.

FEBS letters, 132(2), 231-234 (1981-09-28)

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