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H3780

Sigma-Aldrich

2′-Hydroxyflavanone

≥98%

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Empirical Formula (Hill Notation):
C15H12O3
CAS Number:
Molecular Weight:
240.25
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥98%

form

powder

SMILES string

Oc1ccccc1C2CC(=O)c3ccccc3O2

InChI

1S/C15H12O3/c16-12-7-3-1-5-10(12)15-9-13(17)11-6-2-4-8-14(11)18-15/h1-8,15-16H,9H2

InChI key

KZKWCKFDCPVDFJ-UHFFFAOYSA-N

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Yusuke Iimura et al.
Journal of colloid and interface science, 508, 469-475 (2017-09-02)
The chiral selectivity of β-cyclodextrin (β-CD) in the water/hexane (3.0% THF) two-phase system is studied with chromatography and interfacial tension measurements. Chromatography using silica gel impregnated with aqueous β-CDas the stationary phase reveals that the chiral selectivity of this system
Haiyan Zhang et al.
International journal of clinical and experimental medicine, 8(9), 16955-16959 (2015-12-03)
Gastric carcinoma (GC) is the most common primary malignancy of the digestive tract, with increasing incidence in many countries. 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used to assess inhibition of HepG2 cell proliferation by 2'-hydroxyflavanone. The STAT3 pathway was performed. 2'-hydroxyflavanone
Tomohide Uno et al.
Biopharmaceutics & drug disposition, 36(8), 552-563 (2015-07-30)
CYP2A6 is a major hepatic member of the cytochrome P450 family in humans. Much variation in CYP2A6 levels and activity can be attributed to genetic polymorphisms of this gene. CYP2A6*25 comprises an amino acid substitution, F118L. To clarify the effect
Himangshu Sonowal et al.
Toxicology in vitro : an international journal published in association with BIBRA, 69, 104966-104966 (2020-08-18)
2'-Hydroxyflavanone (2-HF) is a natural flavonoid isolated from citrus fruits. Multiple studies have demonstrated that 2-HF with its anti-proliferative and pro-apoptotic effects prevent the growth of various cancers. Although 2-HF is a well known anti-oxidative and chemopreventive agent, its role
Mariana Silva et al.
Journal of chromatography. A, 1490, 166-176 (2017-02-17)
In this paper a chiral stationary phase (CSP) was prepared by the immobilization of a β-CD derivative (3,5-dimethylphenylcarbamoylated β-CD) onto the surface of amino-functionalized spherical ordered mesoporous silica (denoted as SM) via a urea linkage using the Staudinger reaction. The

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