GEN-7036
Cationic Liposomes for DNA/RNA delivery
DOTAP:Chol:DOPE (1:0.75:0.5)
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UNSPSC Code:
12352211
NACRES:
NA.25
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Quality Level
composition
Deionized RNAse-free Water
concentration
1 mM (DOPE)
1.5 mM (Cholesterol)
2 mM (DOTAP)
impurities
1:0.75:0.5 mol DOTAP:Cholesterol:DOPE
particle size
100 nm
pH
7
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General description
Cationic liposomes are traditionally used for the delivery of genetic materials such as various types of DNA (pDNA, cDNA, CpG DNA, oligonucleotide, antisense oligonucleotide), various types of RNA such as (siRNA, mRNA) and nucleic acid mimics (NAMs). The positive, cationic charge of the lipids is used to neutralize the negative charge of nucleic acids and results in greater encapsulation efficiency, cellular uptake and endosomal delivery.
Application
Drug delivery
Gene delivery
Lipid-protein interactions
Gene delivery
Lipid-protein interactions
Storage and Stability
Liposomes should never be frozen. Liposomes should be stored in the dark at 4°C, except when brought to room temperature for brief periods prior to use.
Liposomes are made under sterile conditions. If you need to take multiple aliquots out of the vial, it is advised to take extreme care in not contaminating the vial. It is recommended to handle the vial under a sterile hood to maintain the sterility of the product. Liposomes should never be frozen. Ice crystals that form during freezing will rupture the lipid membrane of the liposomes and change the size of liposomes particles.
Liposomes are made under sterile conditions. If you need to take multiple aliquots out of the vial, it is advised to take extreme care in not contaminating the vial. It is recommended to handle the vial under a sterile hood to maintain the sterility of the product. Liposomes should never be frozen. Ice crystals that form during freezing will rupture the lipid membrane of the liposomes and change the size of liposomes particles.
Legal Information
Genesome is a trademark of Encapsula NanoSciences
Product of Encapsula Nanosciences
Disclaimer
For research use only
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
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