G6104
Glycinamide hydrochloride
98%
Synonym(s):
2-Aminoacetamide hydrochloride, Aminoacetamide hydrochloride, Glycine amide hydrochloride
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About This Item
Linear Formula:
NH2CH2CONH2 · HCl
CAS Number:
Molecular Weight:
110.54
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
216-789-1
Beilstein/REAXYS Number:
3554199
MDL number:
Assay:
98%
InChI
1S/C2H6N2O.ClH/c3-1-2(4)5;/h1,3H2,(H2,4,5);1H
InChI key
WKNMKGVLOWGGOU-UHFFFAOYSA-N
SMILES string
Cl.NCC(N)=O
assay
98%
mp
204 °C (dec.) (lit.)
Quality Level
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Related Categories
Application
Buffer useful in the physiological pH range.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Gottfried K Schroeder et al.
Biochemistry, 46(13), 4037-4044 (2007-03-14)
As a model for mechanistic comparison with peptidyl transfer within the ribosome, the reaction of aqueous glycinamide with N-formylphenylalanine trifluoroethyl ester (fPhe-TFE) represents an improvement over earlier model reactions involving Tris. The acidity of trifluoroethanol (pKa 12.4) resembles that of
Carolina García-Martínez et al.
The journal of pain : official journal of the American Pain Society, 7(10), 735-746 (2006-10-05)
Vanilloid receptor subunit 1 (TRPV1) is an integrator of physical and chemical stimuli in the peripheral nervous system. This receptor plays a key role in the pathophysiology of inflammatory pain. Thus, the identification of receptor antagonists with analgesic and anti-inflammatory
Lihu Yang et al.
Bioorganic & medicinal chemistry letters, 16(14), 3735-3739 (2006-05-16)
Systematic modification of a screening lead yielded a class of potent glycinamide based CCR2 antagonists. The best compound (55, (2S)-N-[3,5-bis(trifluoromethyl)benzyl]-2-{[2-(1-piperidinyl)ethyl]amino}-2-(3-thienyl)acetamide) displayed good binding affinity (IC50=30 and 39 nM) toward human monocytes and CHO cell expressing human CCR2b, respectively. Functionally, it
Hong Zhao et al.
Bioconjugate chemistry, 17(2), 341-351 (2006-03-16)
The utility of PEGylation for improving therapeutic protein pharmacology would be substantially expanded if the authentic protein drugs could be regenerated in vivo. Diminution of kinetic constants of both enzymes and protein ligands are commonly encountered following permanent bioconjugation with
Irene M Lagoja et al.
Chemistry & biodiversity, 1(1), 106-111 (2006-12-29)
Because of their easy availability and their relative chemical stability, urea, formic acid, and glycine might have played a role in the assembly process of nucleobases. In this paper, a short reaction path is described to prepare hypoxanthine starting from
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