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E10521

Sigma-Aldrich

Ethyl 3-aminobenzoate methanesulfonate

98%

Synonym(s):

MS-222, TS 222, Tricaine, Tricaine methanesulfonate

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About This Item

Linear Formula:
H2NC6H4CO2C2H5·CH3SO3H
CAS Number:
886-86-2
Molecular Weight:
261.29
Beilstein:
3775022
EC Number:
212-956-8
MDL number:
MFCD00013176
UNSPSC Code:
12352100
PubChem Substance ID:
24894382
NACRES:
NA.22

Quality Level

100

Assay

98%

mp

146-149 °C (lit.)

SMILES string

CS(O)(=O)=O.CCOC(=O)c1cccc(N)c1

InChI

1S/C9H11NO2.CH4O3S/c1-2-12-9(11)7-4-3-5-8(10)6-7;1-5(2,3)4/h3-6H,2,10H2,1H3;1H3,(H,2,3,4)

InChI key

FQZJYWMRQDKBQN-UHFFFAOYSA-N

Related Categories

General description

Ethyl 3-aminobenzoate methanesulfonate is mainly used as an anesthetic for fish. It is also used for the euthanasia of all fish species especially zebrafish, which is commonly used in research.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335,H412

Hazard Classifications

Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Anesthesia and euthanasia in zebrafish.
Matthews M
ILAR Journal, 53(2), 192-204 (2012)
A review of tricaine methanesulfonate for anesthesia of fish.
Carter K
Reviews in Fish Biology and Fisheries, 21(1), 51-59 (2011)
Karen E Sullam et al.
The ISME journal, 9(7), 1508-1522 (2015-01-13)
Diverse microbial consortia profoundly influence animal biology, necessitating an understanding of microbiome variation in studies of animal adaptation. Yet, little is known about such variability among fish, in spite of their importance in aquatic ecosystems. The Trinidadian guppy, Poecilia reticulata
Tricaine methane?sulfonate (MS?222) application in fish anaesthesia.
Topic Popovic N
Journal of Applied Ichthyology, 28(4), 553-564 (2012)
Nina De Rocker et al.
Genetics in medicine : official journal of the American College of Medical Genetics, 17(6), 460-466 (2014-09-19)
Submicroscopic deletions of chromosome band 2p25.3 are associated with intellectual disability and/or central obesity. Although MYT1L is believed to be a critical gene responsible for intellectual disability, so far no unequivocal data have confirmed this hypothesis. In this study we
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