D7881
meso-2,3-Dimercaptosuccinic acid
~98%
Synonym(s):
2,3-Dithio-meso-tartaric acid, DIM-SA, DMS, DMSA, Succimer
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About This Item
Linear Formula:
HO2CCH(SH)CH(SH)CO2H
CAS Number:
Molecular Weight:
182.22
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
206-155-2
Beilstein/REAXYS Number:
1725150
MDL number:
Assay:
~98%
Form:
powder
Product Name
meso-2,3-Dimercaptosuccinic acid, ~98%
InChI
1S/C4H6O4S2/c5-3(6)1(9)2(10)4(7)8/h1-2,9-10H,(H,5,6)(H,7,8)/t1-,2+
InChI key
ACTRVOBWPAIOHC-XIXRPRMCSA-N
SMILES string
OC(=O)[C@@H](S)[C@@H](S)C(O)=O
assay
~98%
form
powder
mp
196-198 °C (dec.) (lit.)
storage temp.
−20°C
Quality Level
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Application
meso-2,3-Dimercaptosuccinic acid (DMSA) has been used to form a monolayer on Mg/Ti/Au micromotors to enhance the chelation of toxic heavy metal contaminants (Zn(II), Cd(II) and Pb(II)) from polluted aqueous solutions.
It can be used:
It can be used:
- As a reducing and stabilizing agent to synthesize monolayer-protected gold clusters.
- For terminal carboxylation of the oleylamine coated Fe3O4 nanoparticles, to develop targeted curcumin drug delivery system.
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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One-pot preparation of subnanometer-sized gold clusters via reduction and stabilization by meso-2, 3-dimercaptosuccinic acid.
Negishi Y and Tsukuda T
Journal of the American Chemical Society, 125(14), 4046-4047 (2003)
Erdinç Turk et al.
Biological trace element research, 189(1), 95-108 (2018-08-02)
The present study was conducted to investigate the protective effects of hesperidin (HSP) against sodium arsenite (SA)-induced nephrotoxicity and hepatotoxicity in rats. Thirty-five male Sprague Dawley rats were divided into five groups as follows: control, HSP, SA, SA + HSP 100, and
Yueyue Shi et al.
Frontiers in pharmacology, 11, 556248-556248 (2020-09-29)
Lead (Pb) is an important environmental pollutant. Oxidative stress and the inflammatory response have been postulated as mechanisms involved in lead-induced renal damage. Smilax glabra Roxb. has been used for treatment of heavy-metal poisoning in China for 500 years. We investigated S. glabra
Superparamagnetic Fe3O4 nanoparticles: synthesis by a solvothermal process and functionalization for a magnetic targeted curcumin delivery system.
Qi M, et al.
New. J. Chem., 40(5), 4480-4491 (2016)
Francesca Brero et al.
Nanomaterials (Basel, Switzerland), 10(10) (2020-10-01)
A combination of carbon ions/photons irradiation and hyperthermia as a novel therapeutic approach for the in-vitro treatment of pancreatic cancer BxPC3 cells is presented. The radiation doses used are 0-2 Gy for carbon ions and 0-7 Gy for 6 MV
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