D7631
5,5-Dimethyl-2,4-oxazolidinedione
Synonym(s):
DMO, Dimethadione, NSC 30152
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About This Item
Empirical Formula (Hill Notation):
C5H7NO3
CAS Number:
Molecular Weight:
129.11
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
form
powder
Quality Level
mp
77-80 °C (lit.)
storage temp.
2-8°C
SMILES string
CC1(C)OC(=O)NC1=O
InChI
1S/C5H7NO3/c1-5(2)3(7)6-4(8)9-5/h1-2H3,(H,6,7,8)
InChI key
JYJFNDQBESEHJQ-UHFFFAOYSA-N
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Application
Reactant involved in:
Molecule involved in pharmacological studies including:
- Synthesis of nickel benzoannulated or naphthoannulated β-oxatetraazachlorin complex
- Being used as a cathepsin K inhibitor
Molecule involved in pharmacological studies including:
- Identification of bioequivalent generic substitute for antiepileptic drugs
- Screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis
- Dissolving protein plugs in patients with choledochal cyst / pancreaticobiliary maljunctions
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Deirdre L Zander-Fox et al.
Reproductive biomedicine online, 21(2), 219-229 (2010-07-10)
The preimplantation embryo is highly susceptible to in-vitro stress, and although this does not necessarily perturb blastocyst development, it can significantly affect embryo physiology and the ability to form a viable pregnancy. This study determined that the preimplantation mouse embryo
Catharina Busch et al.
Acta ophthalmologica, 98(7), e801-e806 (2020-03-03)
To investigate clinical baseline characteristics and optical coherence tomography biomarkers predicting visual loss during observation in eyes with diabetic macular oedema (DMO) and good baseline visual acuity (VA). A sub-analysis of a 12-month, retrospective study, including patients with baseline VA
Matias Iglicki et al.
The British journal of ophthalmology, 104(5), 666-671 (2019-08-09)
We aimed to investigate a novel optical coherence tomography (OCT) finding of outer retinal hyperreflective deposits (ORYDs) in patients with naïve diabetic macular oedema (DMO) seen after small gauge pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling. Furthermore
O M Ocon et al.
Journal of dairy science, 86(4), 1194-1200 (2003-05-14)
Feeding cattle diets high in degradable crude protein (CP) or in excess of requirements can reduce fertility and lower uterine pH. Objectives were to determine direct effects of urea and acidic pH during oocyte maturation and embryonic development. For experiment
Sanjeeb Bhandari et al.
Clinical & experimental ophthalmology, 48(4), 462-469 (2019-12-31)
There are limited data on real-world outcomes of cataract surgery in eyes receiving intravitreal treatments for diabetic macular oedema (DMO). Cataract surgery may exacerbate oedema in some eyes with DMO resulting in inferior outcomes. Matched, case-controlled retrospective study of observational
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