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D182257

Sigma-Aldrich

3,5-Dimethyl-1-pyrazolylformaminidium nitrate

97%

Synonym(s):

1-Amidino-3,5-dimethylpyrazole nitrate, 3,5-Dimethylpyrazole-1-carboxamidine nitrate

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About This Item

Empirical Formula (Hill Notation):
C6H10N4 · HNO3
CAS Number:
38184-47-3
Molecular Weight:
201.18
Beilstein:
3599170
EC Number:
253-815-0
MDL number:
MFCD00012715
UNSPSC Code:
12352100
PubChem Substance ID:
24893552
NACRES:
NA.22

Quality Level

200

Assay

97%

form

powder

mp

167-168 °C (dec.) (lit.)

SMILES string

O[N+]([O-])=O.Cc1cc(C)n(n1)C(N)=N

InChI

1S/C6H10N4.HNO3/c1-4-3-5(2)10(9-4)6(7)8;2-1(3)4/h3H,1-2H3,(H3,7,8);(H,2,3,4)

InChI key

AGYXIUAGBLMBGV-UHFFFAOYSA-N

Related Categories

Application

Guanylating reagent for amines.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCBB1318
BCBB1318V
040456/1
08201LE
05401LE

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Journal of Carbohydrate Chemistry, 12, 1173-1173 (1993)
Orakan Hanpanich et al.
Nucleosides, nucleotides & nucleic acids, 39(1-3), 156-169 (2019-10-15)
The cationic copolymer poly(L-lysine)-graft-dextran (PLL-g-Dex) has nucleic acid chaperone-like activity. The copolymer facilitates both DNA hybridization and strand exchange reactions. For these reasons, DNA-based enzyme (DNAzyme) activity is enhanced in the presence of copolymer. In this study, we evaluated activities
Antonia G Miller et al.
Annals of the New York Academy of Sciences, 1043, 195-200 (2005-07-23)
Protein cross-linking via the Maillard reaction with alpha-dicarbonyl compounds has been the subject of intense scrutiny in the literature. We report here a study of the impact of this cross-linking on enzyme function. Protein function following glycation was examined by
L Spero et al.
Biochimica et biophysica acta, 251(3), 345-356 (1971-12-28)
Guanidination of the free amino groups of staphylococcal enterotoxin B with 3,5-dimethyl-1-guanylpyrazole converted 31-32 of 33 epsilon-amino groups and 30% of the N-terminal residue. This product, although markedly reduced in solubility, suffered no gross change in conformation and retained full
A Bernhardt et al.
The journal of peptide research : official journal of the American Peptide Society, 50(2), 143-152 (1997-08-01)
Peptide-4-nitroanilides can be quickly synthesised using an Fmoc-based approach on 2-chlorotritylchloride resin. Preformed building blocks Fmoc-Xaa-NH-Np (Xaa = Cit, Cys, Gln, His, Lys, Orn, Ser, Thr, Tyr, Trp) can be attached via side chain to the 2-chlorotritylchloride linker of the
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