D167800
2,3-Dimethylmaleic anhydride
98%
Synonym(s):
Dimethylmaleic anhydride
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About This Item
Empirical Formula (Hill Notation):
C6H6O3
CAS Number:
Molecular Weight:
126.11
UNSPSC Code:
12162002
NACRES:
NA.23
PubChem Substance ID:
EC Number:
212-165-8
Beilstein/REAXYS Number:
112044
MDL number:
InChI key
MFGALGYVFGDXIX-UHFFFAOYSA-N
InChI
1S/C6H6O3/c1-3-4(2)6(8)9-5(3)7/h1-2H3
SMILES string
CC1=C(C)C(=O)OC1=O
assay
98%
form
flakes
bp
223 °C (lit.)
mp
93-96 °C (lit.)
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Application
Reagent used in the synthesis of maleimides and as an amino group protecting agent for superoxide dismutase.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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J. Controlled Release, 28, 203-203 (1994)
M Gerl et al.
Biochemistry, 27(11), 4089-4096 (1988-05-31)
Apoferritin from horse spleen is composed of 24 subunits that undergo partial dissociation after chemical modification with 2,3-dimethylmaleic anhydride (DMMA), yielding dimeric, trimeric, and tetrameric intermediates, stable at pH 8.5 and 0 degrees C. Deacylation at neutral pH and elevated
A tumor-acidity-activated charge-conversional nanogel as an intelligent vehicle for promoted tumoral-cell uptake and drug delivery.
Jin-Zhi Du et al.
Angewandte Chemie (International ed. in English), 49(21), 3621-3626 (2010-04-15)
Bo Reum Lee et al.
International journal of pharmaceutics, 392(1-2), 78-82 (2010-03-20)
A novel synthetic nanocomplex was constructed from glycol chitosan (GCS) grafted with 2,3-dimethylmaleic anhydride (DMA) (denoted as 'GCD' hereafter) and lysozyme (isoelectric point=10.9) as a model protein. This is a core-shell supramolecular assemble formed through electrostatic interactions between anionic GCD
Hyeong Sup Yu et al.
Pharmaceutics, 11(6) (2019-06-05)
As caterpillars detect the presence of predators and secrete poison, herein, we show an innovative and highly effective cancer therapeutic system using biocompatible chitosan nanofiber (CNf) installed with a pH-responsive motif that senses tumor extracellular pH, pHe, prior to delivering
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