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D167800

Sigma-Aldrich

2,3-Dimethylmaleic anhydride

98%

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Synonym(s):
Dimethylmaleic anhydride
Empirical Formula (Hill Notation):
C6H6O3
CAS Number:
Molecular Weight:
126.11
Beilstein:
112044
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

Assay

98%

form

flakes

bp

223 °C (lit.)

mp

93-96 °C (lit.)

SMILES string

CC1=C(C)C(=O)OC1=O

InChI

1S/C6H6O3/c1-3-4(2)6(8)9-5(3)7/h1-2H3

InChI key

MFGALGYVFGDXIX-UHFFFAOYSA-N

Application

Reagent used in the synthesis of maleimides and as an amino group protecting agent for superoxide dismutase.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Hyeong Sup Yu et al.
Pharmaceutics, 11(6) (2019-06-05)
As caterpillars detect the presence of predators and secrete poison, herein, we show an innovative and highly effective cancer therapeutic system using biocompatible chitosan nanofiber (CNf) installed with a pH-responsive motif that senses tumor extracellular pH, pHe, prior to delivering
C Hikita et al.
The Journal of biological chemistry, 274(25), 17671-17676 (1999-06-11)
When an intercalated epithelial cell line was seeded at low density and allowed to reach confluence, it located the anion exchanger band 3 in the apical membrane and an H+-ATPase in the basolateral membrane. The same clonal cells seeded at
J. Controlled Release, 28, 203-203 (1994)
M Gerl et al.
Biochemistry, 27(11), 4089-4096 (1988-05-31)
Apoferritin from horse spleen is composed of 24 subunits that undergo partial dissociation after chemical modification with 2,3-dimethylmaleic anhydride (DMMA), yielding dimeric, trimeric, and tetrameric intermediates, stable at pH 8.5 and 0 degrees C. Deacylation at neutral pH and elevated
Bo Reum Lee et al.
International journal of pharmaceutics, 392(1-2), 78-82 (2010-03-20)
A novel synthetic nanocomplex was constructed from glycol chitosan (GCS) grafted with 2,3-dimethylmaleic anhydride (DMA) (denoted as 'GCD' hereafter) and lysozyme (isoelectric point=10.9) as a model protein. This is a core-shell supramolecular assemble formed through electrostatic interactions between anionic GCD

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