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Merck
CN

D153303

5,5-Dimethyl-1,3-cyclohexanedione

95%

Synonym(s):

Dimedone, Methone

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About This Item

Linear Formula:
(CH3)2C6H6(=O)2
CAS Number:
Molecular Weight:
140.18
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
204-804-4
Beilstein/REAXYS Number:
471489
MDL number:
Assay:
95%
Form:
powder
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InChI key

BADXJIPKFRBFOT-UHFFFAOYSA-N

InChI

1S/C8H12O2/c1-8(2)4-6(9)3-7(10)5-8/h3-5H2,1-2H3

SMILES string

CC1(C)CC(=O)CC(=O)C1

assay

95%

form

powder

Quality Level

mp

146-148 °C (lit.)

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Application

Part of furannulation strategy for the synthesis of naturally occurring fused 3-methylfurans.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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The Journal of Organic Chemistry, 58, 3960-3960 (1993)
C H Shandrenko et al.
Ukrains'kyi biokhimichnyi zhurnal (1999 ), 83(6), 110-115 (2012-03-01)
A method for endogenous formaldehyde (FA) level evaluation has been worked out. The method involves the administration of dimedone, which forms the stable complex with FA, and the determination of formaldimedone concentration in biological samples by the fluorescence approach. The
Antonio Evidente et al.
Journal of natural products, 74(4), 757-763 (2011-02-24)
Sphaeropsidone and episphaeropsidone are two phytotoxic dimedone methyl ethers produced by Diplodia cupressi, the causal agent of a canker disease of cypress in the Mediterranean area. In this study, eight derivatives obtained by chemical modifications and two natural analogues were
Rebecca N Burns et al.
The Journal of pharmacology and experimental therapeutics, 339(3), 914-921 (2011-09-16)
Reactive oxygen species (ROS), including hydrogen peroxide (H(2)O(2)), have recently been shown to be generated upon agonism of several members of the G protein-coupled receptor (GPCR) superfamily, including β(2)-adrenergic receptors (β(2)ARs). Previously, we have demonstrated that inhibition of intracellular ROS
Candice E Paulsen et al.
Chemistry & biology, 16(2), 217-225 (2009-02-24)
Saccharomyces cerevisiae responds to elevated levels of hydrogen peroxide in its environment via a redox relay system comprising the thiol peroxidase Gpx3 and transcription factor Yap1. In this signaling pathway, a central unresolved question is whether cysteine sulfenic acid modification

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