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Safety Information

D119806

Sigma-Aldrich

Maleic hydrazide

ReagentPlus®, 99%

Synonym(s):

1,2-Dihydro-3,6-pyridazinedione, 3,6-Dihydroxypyridazine, 3,6-Pyridazinediol

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About This Item

Empirical Formula (Hill Notation):
C4H4N2O2
CAS Number:
Molecular Weight:
112.09
Beilstein:
112223
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

product line

ReagentPlus®

Assay

99%

form

powder

autoignition temp.

707 °F

mp

299-301 °C (dec.) (lit.)

SMILES string

O=C1NNC(=O)C=C1

InChI

1S/C4H4N2O2/c7-3-1-2-4(8)6-5-3/h1-2H,(H,5,7)(H,6,8)

InChI key

BGRDGMRNKXEXQD-UHFFFAOYSA-N

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Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 2

Flash Point(F)

closed cup

Flash Point(C)

closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Z Swietlińska et al.
Mutation research, 55(1), 15-30 (1978-01-01)
Since 1950, maleic hydrazide (MH) has been introduced into agriculture as a major commercial herbicide and a depressant of plant growth in numerous circumstances such as suppression of sprouting of vegetables and stored food crops, control of sucker growth on
L Elvia Ruiz Flores et al.
Life sciences, 72(12), 1345-1351 (2003-01-16)
The aim of this investigation was to determine if extracts of Spirulina maxima reduce the genotoxic damage induced by maleic hydrazide (MH) using the Tradescantia biosssay. Two types of extracts from the alga were prepared: an aqueous extract with two
Yanjun Fang et al.
Biosensors & bioelectronics, 24(8), 2323-2327 (2009-03-06)
A novel flow injection chemiluminescence (CL) sensor for the determination of maleic hydrazide (MH) using molecularly imprinted polymer (MIP) as recognition element is reported. The MH-MIP was synthesized by thermal initiated polymerization in methanol, using methacrylic acid (MAA) as functional
Tomás Gichner
Mutation research, 538(1-2), 171-179 (2003-07-02)
The purpose of this study was to determine if mutagen-induced DNA damage is correlated with the frequency of induced recombination events. The alkylating agents ethyl methanesulphonate (EMS) and N-ethyl-N-nitrosourea (ENU), and the plant growth regulator and herbicide maleic hydrazide (MH)
Jolanta Juchimiuk et al.
Journal of applied genetics, 48(2), 99-106 (2007-05-15)
The present study is a rare example of a detailed characterization of chromosomal aberrations by identification of individual chromosomes (or chromosome arms) involved in their formation in plant cells by using fluorescent in situ hybridization (FISH). In addition, the first

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