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CF0046

Sigma-Aldrich

Azidodifluoroacetamide

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Synonym(s):
2-Azido-2,2-difluoroacetamide
Empirical Formula (Hill Notation):
C2H2F2N4O
CAS Number:
Molecular Weight:
136.06
UNSPSC Code:
12352200
NACRES:
NA.06

Quality Level

SMILES string

NC(C(N=[N+]=[N-])(F)F)=O

InChI

1S/C2H2F2N4O/c3-2(4,1(5)9)7-8-6/h(H2,5,9)

InChI key

ISQQWTYWSPQUSN-UHFFFAOYSA-N

Related Categories

General description

Azidodifluoroacetamide is a fluoroalkyl azide reagent active in copper-catalyzed azide-alkyne cycloaddition (click reaction). In addition to its use as a highly fluorinated building block, it can also be functionalized onto biomolecules, advanced materials, or polymers containing an alkyne. It is an effective 19F NMR sensor for these materials, particularly in cases where aqueous solubility is necessary and organic solvents cannot be used.

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Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Articles

Fluorinated azides are a new tool that can be used to introduce fluorinated groups to molecules. These molecules can utilize click chemistry to easily add fluorinated groups.

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