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2-azido-2,2-difluoroacetic acid ethyl ester, Ethyl 2-azido-2,2-difluoroacetate
C4H5F2N3O2
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SMILES string
O=C(OCC)C(N=[N+]=[N-])(F)F
InChI
1S/C4H5F2N3O2/c1-2-11-3(10)4(5,6)8-9-7/h2H2,1H3
InChI key
BISKRTIGSBFIQH-UHFFFAOYSA-N
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General description
Ethyl azidodifluoroacetate is a fluoroalkyl azide reagent active in copper-catalyzed azide-alkyne cycloaddition (click reaction). This reagent allows the unique functionality to afford the transformation of amine substrates to their amide analog, followed by the subsequent click reaction to form amide-triazole functionalities.
Learn more about fluorinated click chemistry
Automate your fluorination reactions with Synple Automated Synthesis Platform (SYNPLE-SC002)
Learn more about fluorinated click chemistry
Automate your fluorination reactions with Synple Automated Synthesis Platform (SYNPLE-SC002)
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Articles
Fluorinated azides are a new tool that can be used to introduce fluorinated groups to molecules. These molecules can utilize click chemistry to easily add fluorinated groups.
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