CF0041
Urea crosslinker – C4-arm, NHS ester (DSBU, BuUrBU)
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Synonym(s):
1,1′-Bis(2,5-dioxo-1-pyrrolidinyl) 4,4′-(carbonyldiimino)bis[butanoate], Disuccinimidyldibutyric urea
Linear Formula:
C17H22N4O9
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form
solid
reaction suitability
reaction type: C-C Bond Formation
reagent type: cross-linking reagent
Related Categories
Application
The ureido-4,4´-dibutyric acid bis(hydroxysuccinimide) ester, also known as DSBU or BuUrBU, is the longest version of MS-cleavable urea-based lysine-lysine reactive homobifunctional cross-linkers, featuring a C4-arm. At neutral or slightly basic pH, it irreversibly crosslinks the neighbouring lysine groups. The presence of the symmetrical urea moiety which is prone to collision-induced dissociation allows for the unambiguous distinguishing of crosslinks in tandem CID-MS experiments.
Legal Information
Product of CF Plus Chemicals.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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