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Merck
CN

C46403

3-Chloro-1-propanol

98%

Synonym(s):

1-Chloro-3-hydroxypropane, Trimethylene chlorohydrin

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About This Item

Linear Formula:
Cl(CH2)3OH
CAS Number:
Molecular Weight:
94.54
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
210-992-9
Beilstein/REAXYS Number:
773655
MDL number:
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Product Name

3-Chloro-1-propanol, 98%

InChI key

LAMUXTNQCICZQX-UHFFFAOYSA-N

InChI

1S/C3H7ClO/c4-2-1-3-5/h5H,1-3H2

SMILES string

OCCCCl

assay

98%

form

liquid

refractive index

n20/D 1.445 (lit.)

bp

160-162 °C (lit.)

density

1.131 g/mL at 25 °C (lit.)

Quality Level

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Application

  • Improved Synthesis of Pheromone Components: 3-chloro-1-propanol is used as a linchpin to connect the two synthetic blocks in the synthesis of 6,14-dimethyl-1-octadecene. It is likely used as a reactant in a chemical reaction to facilitate the coupling of the two synthetic blocks, enabling the formation of the desired compound (Taguri et al., 2010).

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Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

167.0 °F - closed cup

flash_point_c

75 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品
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A R Jones
Reproduction, fertility, and development, 9(6), 577-581 (1997-01-01)
Boar sperm rapidly interconverted dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, produced fructose-1,6-bisphosphate, approximately equilibrium concentrations of fructose 6-phosphate and glucose 6-phosphate but not glycerol or glycerol 3-phosphate. In the presence of 3-chloro-1-hydroxypropanone, an inhibitor of stage 2 of the glycolytic pathway
A R Jones et al.
Journal of reproduction and fertility, 111(2), 285-290 (1998-02-14)
When incubated in the absence of exogenous substrates, washed boar spermatozoa maintained a high energy charge potential (ECP) for at least 5 h. Addition of 3-chloro-1-hydroxypropanone, an inhibitor of triosephosphate isomerase and glyceraldehyde 3-phosphate dehydrogenase, at any time caused the
Nico E A Cousens et al.
Faraday discussions, 199, 63-73 (2017-05-06)
Electrowetting-on-dielectric devices typically have operating voltages of 10-20 V. A reduction in the operating voltage could greatly reduce the energy consumption of these devices. Herein, fully reversible one-electrolyte electrowetting of a droplet on a solid metal surface is reported for
T Yamanaka et al.
The journal of physical chemistry. A, 112(13), 2773-2781 (2008-03-12)
FTIR smog chamber techniques were used to measure k(Cl+n-C3H7OH) = (1.74 +/- 0.15) x 10-10 and k(Cl+CH2ClCH2CH2OH) = (7.54 +/- 0.73) x 10-11 cm3 molecule-1 s-1 in 700 Torr of N2 at 296 K. The reaction of Cl with n-C3H7OH
T G Cooper et al.
International journal of andrology, 23(4), 243-247 (2000-07-25)
3-(36)Chloro-1-hydroxypropanone (CHOP), a specific inhibitor of sperm glycolysis in vitro, is rapidly metabolized by the male rat to alpha-chlorohydrin, 3-chlorolactate and the inhibitory sperm metabolite, 3-chlorolactaldehyde, presumably all being of the (S)-configuration. The dimethyl ketal of (36)Cl-CHOP [3-(36)Cl-dimethyl-CHOP] is rapidly

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