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Key Documents

Safety Information

C44400

Sigma-Aldrich

2-Amino-4-chlorophenol

97%

Synonym(s):

5-Chloro-2-hydroxyaniline

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About This Item

Linear Formula:
H2NC6H3(Cl)OH
CAS Number:
Molecular Weight:
143.57
Beilstein:
774859
EC Number:
MDL number:
UNSPSC Code:
12352100
eCl@ss:
39050738
PubChem Substance ID:
NACRES:
NA.22

Assay

97%

form

powder

mp

136-141 °C (lit.)

SMILES string

Nc1cc(Cl)ccc1O

InChI

1S/C6H6ClNO/c7-4-1-2-6(9)5(8)3-4/h1-3,9H,8H2

InChI key

SWFNPENEBHAHEB-UHFFFAOYSA-N

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Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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Marcelo N N Vieira et al.
Cell biochemistry and biophysics, 44(3), 549-553 (2006-05-09)
Protein amyloid aggregation is associated with a number of important human pathologies, but the precise mechanisms underlying the toxicity of amyloid aggregates are still incompletely understood. In this context, drugs capable of blocking or interfering with the aggregation of amyloidogenic
S Ramalingam et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 104, 337-351 (2013-01-01)
The spectra (FT-IR and FT-Raman) of the present compound; 2-amino-4-chlorophenol (2A4CP) were recorded in the range of 4000-100 cm(-1). All the computational calculations were made in the ground state using the HF and DFT (B3LYP and B3PW91) methods with 6-31++G(d,p)
M M Ellaithy et al.
Farmaco (Societa chimica italiana : 1989), 58(4), 337-342 (2003-05-03)
2-Amino-4-chlorophenol was found to be the alkaline induced degradation product and the synthetic precursor of chlorzoxazone. The aim of this work is to study different factors affecting the degradation process due to the high toxicity of 2-amino-4-chlorophenol. Chlorzoxazone was found
Mustafa Tuzen et al.
Journal of hazardous materials, 158(1), 137-141 (2008-02-26)
A separation-preconcentration procedure based on the coprecipitation of lead(II) and chromium(III) ions with copper(II)-5-chloro-2-hydroxyaniline system has been developed. Effects of pH, sample volume and interferences on the recovery of the metal ions were investigated. The detection limits corresponding to three
Industrial contact dermatitis due to nitro and amino derivatives. 2nd report: experimental study of cross sensitivities of amino derivatives.
S Naniwa
The Journal of dermatology, 9(5), 367-373 (1982-10-01)

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