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C13408

O-(Carboxymethyl)hydroxylamine hemihydrochloride

Name: <I>O</I>-(Carboxymethyl)hydroxylamine hemihydrochloride
Brand: ALDRICH

98%

Synonym(s):

Carboxymethoxylamine hemihydrochloride, (Aminooxy)acetic acid hemihydrochloride, (Carboxymethoxy)amine hemihydrochloride, Hydroxylamine-O-acetic acid hemihydrochloride

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About This Item

Linear Formula:

NH₂OCH₂COOH · 0.5HCl

CAS Number:

2921-14-4

Molecular Weight:

109.30

Beilstein:

3680528

EC Number:

220-862-3

MDL number:

MFCD00012955

UNSPSC Code:

12352100

PubChem Substance ID:

24892403

NACRES:

NA.22

biological source

synthetic (organic)

Quality Level

200

Assay

98%

form

crystalline powder
powder or crystals

mp

156 °C (dec.) (lit.)

solubility

water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

storage temp.

2-8°C

SMILES string

Cl.NOCC(O)=O.NOCC(O)=O

InChI

1S/2C2H5NO3.ClH/c2*3-6-1-2(4)5;/h2*1,3H2,(H,4,5);1H

InChI key

KBXIJIPYZKPDRU-UHFFFAOYSA-N

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Organic Building Blocks

Application

O-(Carboxymethyl)hydroxylamine hemihydrochloride can be used as a reactant to synthesize oximes via condensation with aldehydes and ketones. It can also be used as a potent inhibitor of (pyridoxal 5’-phosphate) PLP-dependent β-lyases.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Tetrahedron Letters, 34, 4347-4347 (1993)

Characterization of a 5'-aldehyde terminus resulting from the oxidative attack at C5 `of a 2-deoxyribose on DNA

Angeloff A, et al.

Chemical Research in Toxicology, 14, 1413-1420 (2001)

Tissue distribution of cytosolic beta-elimination reactions of selenocysteine Se-conjugates in rat and human

Rooseboom M, et al.

Chemico-Biological Interactions, 140, 243-264 (2002)

Computational models applied to metabolomics data hints at the relevance of glutamine metabolism in breast cancer.

Lucía Trilla-Fuertes et al.

BMC cancer, 20(1), 307-307 (2020-04-16)

Metabolomics has a great potential in the development of new biomarkers in cancer and it has experiment recent technical advances. In this study, metabolomics and gene expression data from 67 localized (stage I to IIIB) breast cancer tumor samples were

Synthesis and in vitro antibacterial properties of 2-(3-bromo-5-isoxazolylideneamino-oxy)acetamido-beta-lactam derivatives.

A Sala et al.

Farmaco (Societa chimica italiana : 1989), 46(7-8), 887-897 (1991-07-01)

The synthesis of new 2-(3-bromo-5-isoxazolylideneamino-oxy)acetic acids and their condensation derivatives with suitable beta-lactam nuclei is reported. Their antibacterial properties have been tested in vitro. An interesting activity against Gram-positive bacteria including beta-lactamase-producing microorganisms was found among the cephalosporanic acid derivatives.

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