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Merck
CN

C106402

N-Cyclohexyl-N′-(2-morpholinoethyl)carbodiimide methyl-p-toluenesulfonate

95%

Synonym(s):

4-[2-[(Cyclohexylcarbonimidoyl)amino]ethyl]-4-methylmorpholinium p-toluenesulfonate, N-Cyclohexyl-N′-(β-[N-methylmorpholino]ethyl)carbodiimide p-toluenesulfonate salt, CMC, CMC metho-p-toluenesulfonate, Morpho CDI

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About This Item

Empirical Formula (Hill Notation):
C14H26N3O · C7H7O3S
CAS Number:
2491-17-0
Molecular Weight:
423.57
NACRES:
NA.26
PubChem Substance ID:
329774842
UNSPSC Code:
12352111
EC Number:
219-650-3
MDL number:
MFCD00011979
Assay:
95%
Form:
crystals

Key Documents

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InChI key

GBCAVSYHPPARHX-UHFFFAOYSA-M

InChI

1S/C14H26N3O.C7H8O3S/c1-17(9-11-18-12-10-17)8-7-15-13-16-14-5-3-2-4-6-14;1-6-2-4-7(5-3-6)11(8,9)10/h14H,2-12H2,1H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1

SMILES string

Cc1ccc(cc1)S([O-])(=O)=O.C[N+]2(CCOCC2)CCN=C=NC3CCCCC3

assay

95%

form

crystals

mp

113-115 °C (lit.)

Quality Level

200

Application

Employed in a facile sequencing technique for pseudouridylate residues in RNA.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SDBB6901
SDBB2521
STBL1691
STBK9581
STBK5448

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Carola Schafer et al.
Malaria journal, 17(1), 370-370 (2018-10-20)
Plasmodium vivax is the most geographically widespread of the human malaria parasites, causing 50,000 to 100,000 deaths annually. Plasmodium vivax parasites have the unique feature of forming dormant liver stages (hypnozoites) that can reactivate weeks or months after a parasite-infected
A Bakin et al.
Biochemistry, 32(37), 9754-9762 (1993-09-21)
A new technique has been developed for the facile location of pseudouridylate (psi) residues in any RNA molecule. The method uses two known modification procedures which in combination uniquely identify U residues which have been converted into psi. The first
A L Bricker et al.
Journal of bacteriology, 181(11), 3587-3590 (1999-05-29)
High-level expression of the major pilus subunit (PapA) of uropathogenic strains of Escherichia coli results in part from the unusually long lifetime of the mRNA that encodes this protein. Here we report that the longevity of papA mRNA derives in
K G Patteson et al.
Nucleic acids research, 29(10), E49-E49 (2001-05-23)
A new method using matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the direct analysis of the mass-silent post-transcriptionally modified nucleoside pseudouridine in nucleic acids has been developed. This method utilizes 1-cyclohexyl-3-(2-morpholinoethyl)carbodiimide to derivatize pseudouridine residues. After chemical derivatization all pseudouridine
P V Sergiev et al.
Journal of molecular biology, 299(2), 379-389 (2000-06-22)
The proximity of loop D of 5 S rRNA to two regions of 23 S rRNA, domain II involved in translocation and domain V involved in peptide bond formation, is known from previous cross-linking experiments. Here, we have used site-directed
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