C101400
1,2-Cyclohexanedione
97%
Synonym(s):
1,2-Dioxocyclohexane, Cyclohexan-1,2-dione
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About This Item
Linear Formula:
C6H8(=O)2
CAS Number:
Molecular Weight:
112.13
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
212-155-3
Beilstein/REAXYS Number:
507419
MDL number:
Assay:
97%
Form:
solid
Quality Level
InChI key
OILAIQUEIWYQPH-UHFFFAOYSA-N
InChI
1S/C6H8O2/c7-5-3-1-2-4-6(5)8/h1-4H2
SMILES string
O=C1CCCCC1=O
assay
97%
form
solid
bp
193-195 °C (lit.)
mp
34-38 °C (lit.)
storage temp.
2-8°C
Gene Information
human ... ACHE(43), BCHE(590), CES1(1066)
Related Categories
Application
Specific reagent for arginine residues.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
No data available
flash_point_c
No data available
ppe
Eyeshields, Gloves, type N95 (US)
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D Scott Wilbur et al.
Bioconjugate chemistry, 13(3), 611-620 (2002-05-16)
Recombinant streptavidin (rSAv) is of interest as a carrier of alpha-emitting radionuclides in pretargeting protocols for cancer therapy. Due to the inherently high kidney localization of rSAv, modification of this protein is required before it can be useful in pretargeting.
Andres De la Rossa et al.
Nature neuroscience, 16(2), 193-200 (2013-01-08)
The molecular mechanisms that control how progenitors generate distinct subtypes of neurons, and how undifferentiated neurons acquire their specific identity during corticogenesis, are increasingly understood. However, whether postmitotic neurons can change their identity at late stages of differentiation remains unknown.
Alma Steinbach et al.
The FEBS journal, 279(7), 1209-1219 (2012-02-09)
The thiamine diphosphate (ThDP) dependent flavoenzyme cyclohexane-1,2-dione hydrolase (CDH) (EC 3.7.1.11) catalyses a key step of a novel anaerobic degradation pathway for alicyclic alcohols by converting cyclohexane-1,2-dione (CDO) to 6-oxohexanoate and further to adipate using NAD(+) as electron acceptor. To
C Cervenanský et al.
European journal of biochemistry, 229(1), 270-275 (1995-04-01)
The West African green mamba, Dendroaspis angusticeps, has two toxins, fasciculins, that are non-competitive inhibitors of acetylcholinesterase. Arginine residues of fasciculin 2 were modified with 1,2-cyclohexanedione. Two of these residues, Arg24 and Arg37, reacted very slowly or not at all.
S Adak et al.
The Biochemical journal, 314 ( Pt 3), 985-991 (1996-03-15)
The plausible role of arginine and tyrosine residues at the active side of horseradish peroxidase (HRP) in aromatic donor (guaiacol) oxidation was probed by chemical modification followed by characterization of the modified enzyme. The arginine-specific reagents phenylglyoxal (PGO), 2,3-butanedione and
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