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Key Documents

Safety Information

B88608

Sigma-Aldrich

tert-Butyl acetoacetate

reagent grade, 97%

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About This Item

Linear Formula:
CH3COCH2COOC(CH3)3
CAS Number:
Molecular Weight:
158.19
Beilstein:
1680303
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

grade

reagent grade

Assay

97%

form

liquid

refractive index

n20/D 1.419 (lit.)

bp

71-72 °C/11 mmHg (lit.)

density

0.954 g/mL at 25 °C (lit.)

storage temp.

−20°C

SMILES string

CC(=O)CC(=O)OC(C)(C)C

InChI

1S/C8H14O3/c1-6(9)5-7(10)11-8(2,3)4/h5H2,1-4H3

InChI key

JKUYRAMKJLMYLO-UHFFFAOYSA-N

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

150.8 °F - closed cup

Flash Point(C)

66 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Meghan C Drummond et al.
Nature communications, 6, 6873-6873 (2015-04-22)
The maintenance of sensory hair cell stereocilia is critical for lifelong hearing; however, mechanisms of structural homeostasis remain poorly understood. Conflicting models propose that stereocilia F-actin cores are either continually renewed every 24-48 h via a treadmill or are stable, exceptionally
Jordan M Spatz et al.
The Journal of biological chemistry, 290(27), 16744-16758 (2015-05-09)
Although bone responds to its mechanical environment, the cellular and molecular mechanisms underlying the response of the skeleton to mechanical unloading are not completely understood. Osteocytes are the most abundant but least understood cells in bones and are thought to
Ying Wang et al.
Endocrinology, 155(5), 1970-1981 (2014-03-08)
FSH is an essential regulator of mammalian reproduction. Its synthesis by pituitary gonadotrope cells is regulated by multiple endocrine and paracrine factors, including TGFβ superfamily ligands, such as the activins and inhibins. Activins stimulate FSH synthesis via transcriptional regulation of
Hong Xie et al.
Oncotarget, 5(20), 10048-10057 (2014-10-11)
Telomerase activation through the induction of its catalytic component TERT is essential in carcinogenesis. The regulatory mechanism and clinical significance underlying cancer-specific TERT expression have been extensively investigated in various human malignancies, but little is known about these in Merkel
Joseph G Crompton et al.
Cancer research, 75(2), 296-305 (2014-11-30)
Adoptive cell therapy (ACT) using autologous tumor-infiltrating lymphocytes (TIL) results in complete regression of advanced cancer in some patients, but the efficacy of this potentially curative therapy may be limited by poor persistence of TIL after adoptive transfer. Pharmacologic inhibition

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