B3128
S-Butyrylthiocholine chloride
crystalline
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About This Item
Empirical Formula (Hill Notation):
C9H20ClNOS
CAS Number:
Molecular Weight:
225.78
UNSPSC Code:
12352100
PubChem Substance ID:
EC Number:
244-731-5
MDL number:
InChI key
QYNZLUZQWOCGCH-UHFFFAOYSA-M
InChI
1S/C9H20NOS.ClH/c1-5-6-9(11)12-8-7-10(2,3)4;/h5-8H2,1-4H3;1H/q+1;/p-1
SMILES string
Cl.CCCC(=O)SCC[N](C)(C)C
form
crystalline
storage temp.
2-8°C
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Sylwester Ślusarczyk et al.
International journal of molecular sciences, 21(12) (2020-06-27)
Inhibition of cholinesterases remains one of a few available treatment strategies for neurodegenerative dementias such as Alzheimer's disease and related conditions. The current study was inspired by previous data on anticholinesterase properties of diterpenoids from Perovskia atriplicifolia and other Lamiaceae
Prashamsa Koirala et al.
Molecules (Basel, Switzerland), 23(4) (2018-03-31)
The current study assesses the antioxidant effects of two similar isoflavonoids isolated from Pueraria lobata, coumestrol and puerarol, along with the cholinergic and amyloid-cascade pathways to mitigate Alzheimer's disease (AD). Antioxidant activity was evaluated via 1,1-diphenyl-2-picryhydrazyl (DPPH) and peroxynitrite (ONOO-)
F Sezer Senol et al.
Phytochemistry, 133, 33-44 (2016-11-08)
Cholinesterase inhibition is one of the most treatment strategies against Alzheimer's disease (AD) where metal accumulation is also strongly associated with pathology of the disease. In the current study, we assessed inhibitory effect against acetyl- (AChE) and butyrylcholinesterase (BChE) and
Archana S Gurjar et al.
Bioorganic & medicinal chemistry, 26(8), 1511-1522 (2018-02-13)
Alzheimer's disease (AD) is a progressive neurodegenerative disorder with multiple factors associated with its pathogenesis. Our strategy against AD involves design of multi-targeted 2-substituted-4,5-diphenyl-1H-imidazole analogues which can interact and inhibit AChE, thereby, increasing the synaptic availability of ACh, inhibit BuChE
Onur Bender et al.
PloS one, 13(6), e0197815-e0197815 (2018-06-05)
The genus Hypericum is one of the most popular genera in both traditional medicine and scientific platform. This study is designed to provide conceptual insights on the biological potential and chemical characterization of H. salsugineum, which is endemic to Turkey.
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