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Key Documents

A8784

Sigma-Aldrich

N-Acetylputrescine hydrochloride

≥98% (TLC)

Synonym(s):

Monoacetyl-1,4-diaminobutane hydrochloride, N-(4-Aminobutyl)acetamide hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C6H14N2O · HCl
CAS Number:
Molecular Weight:
166.65
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥98% (TLC)

form

solid

storage temp.

2-8°C

SMILES string

Cl.CC(=O)NCCCCN

InChI

1S/C6H14N2O.ClH/c1-6(9)8-5-3-2-4-7;/h2-5,7H2,1H3,(H,8,9);1H

InChI key

XBECFEJUQZXMFE-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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S B Rao et al.
Journal of biochemical toxicology, 5(1), 23-32 (1990-01-01)
The mechanism by which chlordecone (CD) amplifies the hepatotoxicity of halomethanes such as CCl4, CHCl3, and BrCCl3 has been a subject of intense study. Recent work has shown that suppression of hepatocellular regeneration leads to accelerated progression of liver injury
M M Abdel-Monem et al.
Journal of chromatography, 222(3), 363-370 (1981-03-13)
A procedure is described for the determination of monoacetylputrescine, N1-acetyl-spermidine and N8-acetylspermidine in human urine. The procedure is based on the high-performance liquid chromatographic separation of the 5-dimethylaminonaphthalene-1-sulfonyl (dansyl) derivatives of these amines using two different chromatographic modes. Monoacetyl-1,6-diaminohexane was
W J Hrushesky et al.
Cancer research, 43(8), 3944-3947 (1983-08-01)
Polyamines are small, highly charged, organic cations of possible regulatory importance in RNA-dependent protein synthesis, the production of which reflects cellular growth and division. The cytokinetics of normal cell populations is circadian rhythmic. This is reflected by a circadian rhythmicity
Jeong Ah Byun et al.
Cancer letters, 273(2), 300-304 (2008-09-23)
Polyamines are essential for cell growth and differentiation of cells and its increased production is observed in many cancers. Due to one of key enzymes in polyamine synthesis ornithine decarboxylase is stimulated by estrogens in breast cancer cells, the polyamine
J L Ryan et al.
Journal of immunology (Baltimore, Md. : 1950), 132(4), 1888-1891 (1984-04-01)
Fully acetylated diamines hexamethylenebisacetamide (HMBA) and diacetylputrescine (tetramethylenebisacetamide, TMBA) cause inhibition of murine B lymphocyte activation in the absence of ruminant serum. Mitogenesis induced by LPS, LAP, and 8-BrcGMP was profoundly inhibited in the presence of 3 mM HMBA and

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