A8060
Acrylic acid N-hydroxysuccinimide ester
≥90%, for peptide synthesis
Synonym(s):
N-Acryloxysuccinimide
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About This Item
Empirical Formula (Hill Notation):
C7H7NO4
CAS Number:
Molecular Weight:
169.13
UNSPSC Code:
12352005
PubChem Substance ID:
NACRES:
NA.22
MDL number:
Product Name
Acrylic acid N-hydroxysuccinimide ester, ≥90% (HPLC)
SMILES string
C=CC(=O)ON1C(=O)CCC1=O
InChI
1S/C7H7NO4/c1-2-7(11)12-8-5(9)3-4-6(8)10/h2H,1,3-4H2
InChI key
YXMISKNUHHOXFT-UHFFFAOYSA-N
assay
≥90% (HPLC)
form
solid
application(s)
peptide synthesis
storage temp.
2-8°C
Quality Level
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Application
Acrylic acid N-hydroxysuccinimide ester (NAS) is a general acrylating agent that is used in the synthesis of:
- Acrylated hyaluronic acid (HA) hydrogel for bone regeneration applications.
- Injectable, biodegradable, and thermosensitive copolymers for tissue engineering.
- Imidazole-based biocompatible, aqueous quantum dots (QDs).
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Bone regeneration using hyaluronic acid-based hydrogel with bone morphogenic protein-2 and human mesenchymal stem cells.
Kim J, et al.
Biomaterials, 28(10), 1830-1837 (2007)
Compact biocompatible quantum dots via RAFT-mediated synthesis of imidazole-based random copolymer ligand.
Liu W, et al.
Journal of the American Chemical Society, 132(2), 472-483 (2009)
Avin Ramaiya et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(41), 10894-10899 (2017-10-05)
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Protein-reactive, thermoresponsive copolymers with high flexibility and biodegradability.
Guan J, et al.
Biomacromolecules, 9(4), 1283-1292 (2008)
Fred Y Shen et al.
Nature communications, 11(1), 4632-4632 (2020-09-17)
Mapping neuroanatomy is a foundational goal towards understanding brain function. Electron microscopy (EM) has been the gold standard for connectivity analysis because nanoscale resolution is necessary to unambiguously resolve synapses. However, molecular information that specifies cell types is often lost
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