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A79604

4-Aminosalicylic acid

Name: 4-Aminosalicylic acid
Brand: ALDRICH

99%, for peptide synthesis

Synonym(s):

4-Amino-2-hydroxybenzoic acid, PAS

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About This Item

Linear Formula:

H₂NC₆H₃-2-(OH)CO₂H

CAS Number:

65-49-6

Molecular Weight:

153.14

NACRES:

NA.22

PubChem Substance ID:

24891299

UNSPSC Code:

12352106

EC Number:

200-613-5

MDL number:

MFCD00007789

Beilstein/REAXYS Number:

473071

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Properties

Product Name

4-Aminosalicylic acid, 99%

assay

99%

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

color

white to beige

mp

135-145 °C (lit.)

application(s)

peptide synthesis

SMILES string

Nc1ccc(C(O)=O)c(O)c1

InChI

1S/C7H7NO3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,9H,8H2,(H,10,11)

InChI key

WUBBRNOQWQTFEX-UHFFFAOYSA-N

Gene Information

human ... PTPN1(5770)

Description

Application

4-Aminosalicylic acid (4-ASA) can be used in the synthesis of:

Azo derivatives of 4-ASA with anti-inflammatory effects.
Ammonium 4-aminosalicylate salt polymorphs which are used as pharmaceutical ingredients.
Salicylic acid-triazole analogs which are used as quorum sensing inhibitors against Pseudomonas aeruginosa.

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Design, Synthesis and Biological Evaluation of Triazole-Containing 2-Phenylindole and Salicylic Acid as Quorum Sensing Inhibitors Against Pseudomonas aeruginosa.

Srinivasarao S, et al.

ChemistrySelect, 3(32), 9170-9180 (2018)

Polymorphic ammonium salts of the antibiotic 4-aminosalicylic acid.

Andre V, et al.

Crystal Growth & Design, 12(6), 3082-3090 (2012)

Rituximab, plasma exchange and intravenous immunoglobulins as a new treatment strategy for severe HLA alloimmune platelet refractoriness.

Joan Cid et al.

Platelets, 26(2), 190-194 (2014-05-29)

Platelet refractoriness (PR) due to HLA alloimmunization is a common and serious complication of patients receiving long-term packed red blood cell and platelet transfusions. Although most alloimmunized patients will respond to HLA-matched platelets, 20-50% of patients will remain refractory even

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Global Trade Item Number

SKU	GTIN
A79604-100G	04061833390818
A79604-5G	04061833390849