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A77903

Sigma-Aldrich

1-Aminopyrene

97%

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Synonym(s):
1-Pyrenamine, 3-Aminopyrene
Empirical Formula (Hill Notation):
C16H11N
CAS Number:
Molecular Weight:
217.27
Beilstein:
1875737
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

form

powder

mp

115-117 °C (lit.)

SMILES string

Nc1ccc2ccc3cccc4ccc1c2c34

InChI

1S/C16H11N/c17-14-9-7-12-5-4-10-2-1-3-11-6-8-13(14)16(12)15(10)11/h1-9H,17H2

InChI key

YZVWKHVRBDQPMQ-UHFFFAOYSA-N

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Application

  • Synthesis and evaluation of aromatic stationary phases based on linear solvation energy relationship model for expanded application in supercritical fluid chromatography.: Explores the use of 1-Aminopyrene in the development of advanced stationary phases for chromatography, enhancing the efficiency and application range in pharmaceutical and environmental analysis (Ge et al., 2024).
  • Two-Dimensional Porphyrinic Metal-Organic Framework Composites as a Photocatalytic Platform for Chemoselective Hydrogenation.: Highlights the integration of 1-Aminopyrene into metal-organic frameworks, providing a new avenue for creating highly efficient photocatalytic systems for organic synthesis, relevant to both academic research and industrial chemical manufacturing (Dong et al., 2023).
  • Exploiting and Engineering Neuroglobin for Catalyzing Carbene N-H Insertions and the Formation of Quinoxalinones.: Discusses the role of 1-Aminopyrene in enhancing enzymatic reactions within engineered proteins, paving the way for novel synthetic pathways in pharmaceutical research (Sun et al., 2023).

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Chemical research in toxicology, 11(4), 335-341 (1998-05-05)
While the one-ring amine aniline (AN) has only slight genetic activity, the polycyclic aromatic amines 2-aminofluorene (AF) and 1-aminopyrene (AP) are significant mutagens and carcinogens. Moreover, the bulkier AP is more mutagenic per adduct than AF in the tetracycline-resistance gene
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