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Key Documents

A76109

Sigma-Aldrich

3-Amino-1-propanesulfonic acid

97%

Synonym(s):

3APS, Homotaurine, Tramiprosate

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About This Item

Linear Formula:
H2N(CH2)3SO3H
CAS Number:
Molecular Weight:
139.17
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

form

solid

mp

293 °C (dec.) (lit.)

SMILES string

NCCCS(O)(=O)=O

InChI

1S/C3H9NO3S/c4-2-1-3-8(5,6)7/h1-4H2,(H,5,6,7)

InChI key

SNKZJIOFVMKAOJ-UHFFFAOYSA-N

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1 of 4

This Item
Z742494Z742496Z679984
feature

accuracy± 0.3 °C, temperature uniformity± 0.2 °C, incremental 0.1 °C

feature

accuracy± 0.3 °C, incremental 0.1 °C, temperature uniformity± 0.2 °C

feature

accuracy± 0.3 °C, incremental 0.1 °C, temperature uniformity± 0.2 °C

feature

-

capacity

, holds 1 block

capacity

, holds 1 block

capacity

, holds 1 block

capacity

, holds 1 block

parameter

+5 °C temp. range (100 °C)

parameter

+5 °C temp. range (100 °C)

parameter

+5 °C temp. range (100 °C)

parameter

5-100 °C temp. range

W × D × H

4 in. (10.5 cm) × 6 in. (15 cm) × 4.5 in. (11.5 cm)

W × D × H

4 in. (10.5 cm) × 6 in. (15 cm) × 4.5 in. (11.5 cm)

W × D × H

4 in. (10.5 cm) × 6 in. (15 cm) × 4.5 in. (11.5 cm)

W × D × H

-

manufacturer/tradename

Benchmark Scientific BSH200-HL-E

manufacturer/tradename

Benchmark Scientific BSH200-HL

manufacturer/tradename

Benchmark Scientific BSH200-HL-E-UK

manufacturer/tradename

Benchmark Scientific BSH200

packaging

pkg of 1

packaging

pkg of 1

packaging

pkg of 1

packaging

-

Application

Important gabamimetic agent-evokes neurological responses similar to those elicited by γ-aminobutyric acid (GABA).[1][2][3][4]

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Eric Martineau et al.
Journal of the American Society for Mass Spectrometry, 21(9), 1506-1514 (2010-06-29)
This paper describes an efficient and reproducible screening method for identifying low molecular weight compounds that bind to amyloid beta peptides (Abeta) peptides using electrospray ionization mass spectrometry (ESI-MS). Low molecular weight compounds capable of interacting with soluble Abeta may
Francine Gervais et al.
Neurobiology of aging, 28(4), 537-547 (2006-05-06)
Amyloid beta-peptide (Abeta) is a major constituent of senile plaques in Alzheimer's disease (AD). Neurotoxicity results from the conformational transition of Abeta from random-coil to beta-sheet and its oligomerization. Among a series of ionic compounds able to interact with soluble
M Foster Olive et al.
European journal of pharmacology, 437(1-2), 55-61 (2002-02-28)
The purpose of the present study was to determine the acute effects of the anticraving compound acamprosate (calcium acetylhomotaurinate) and the closely related compound homotaurine on ethanol intake and ethanol-stimulated dopamine release in the nucleus accumbens. Male rats were treated
Xiao-Dong Hu et al.
Neuropharmacology, 50(2), 238-244 (2005-12-06)
The benzodiazepine diazepam impairs memory and long-term potentiation (LTP) in the hippocampus. Here, we investigate the effect of diazepam on LTP of C-fiber evoked field potentials in spinal dorsal horn, which is relevant to pathological pain. LTP of C-fiber evoked
Steven M Greenberg et al.
Alzheimer disease and associated disorders, 20(4), 269-274 (2006-11-30)
No treatments have been identified to lower the risk of intracerebral hemorrhage due to cerebral amyloid angiopathy (CAA). A potential approach to prevention is the use of agents that interfere with the pathogenic cascade initiated by the beta-amyloid peptide (Abeta).

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