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Merck
CN

A7256

DL-Norepinephrine hydrochloride

crystalline, ≥97% (TLC)

Synonym(s):

(±)-1-(3,4-Dihydroxyphenyl)-2-aminoethanol hydrochloride, (±)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol hydrochloride, DL-Arterenol hydrochloride, DL-Noradrenaline hydrochloride

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About This Item

Linear Formula:
(HO)2C6H3CH(OH)CH2NH2 · HCl
CAS Number:
55-27-6
Molecular Weight:
205.64
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
57653879
EC Number:
200-229-8
Beilstein/REAXYS Number:
3707003
MDL number:
MFCD00012880

Key Documents

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Product Name

DL-Norepinephrine hydrochloride, crystalline, ≥97% (TLC)

SMILES string

NCC(C1=CC(O)=C(C=C1)O)O.Cl

InChI key

FQTFHMSZCSUVEU-UHFFFAOYSA-N

InChI

1S/C8H11NO3.ClH/c9-4-8(12)5-1-2-6(10)7(11)3-5;/h1-3,8,10-12H,4,9H2;1H

assay

≥97% (TLC)

form

crystalline

color

off-white to tan

solubility

water: soluble 50 mg/mL, clear to slightly hazy, faintly yellow to brownish-yellow

storage temp.

−20°C

Quality Level

200

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Application

DL-Norepinephrine hydrochloride is suitable adrenergic drug used in the following studies:
  • To investigate the effects of adrenergic drugs on lantern of larval fly.
  • To evaluate the ability of α-adrenergic stimulation in the presence of elevated calcium levels to induce delayed after depolarizations and triggered activity in Purkinje fibers isolated from cat hearts.
  • Simultaneous reduction and surface functionalization of graphene oxide by a one-step poly(norepinephrine) functionalization.

General description

DL-Norepinephrine hydrochloride is an adrenergic drug.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

Lot/Batch Number
MKCW3219
MKCQ5284
MKCP5464
MKCL5708
MKCG2176

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Yining Chen et al.
Journal of neurophysiology, 125(6), 2397-2407 (2021-05-13)
Sensory learning during critical periods in development has lasting effects on behavior. Neuromodulators like dopamine and norepinephrine (NE) have been implicated in various forms of sensory learning, but little is known about their contribution to sensory learning during critical periods.
S Kimura et al.
Circulation, 70(6), 1074-1082 (1984-12-01)
We studied the ability of alpha-adrenergic stimulation to induce delayed afterdepolarizations and triggered activity in Purkinje fibers from cat hearts in the presence of an elevated Ca++ concentration. Delayed afterdepolarizations could not be induced at drive cycle lengths of 200
Effect of adrenergic drugs on the lantern of the larval Photuris firefly.
A D Carlson
The Journal of experimental biology, 48(2), 381-387 (1968-04-01)
Simultaneous Reduction and Surface Functionalization of Graphene Oxide by Mussel-Inspired Chemistry.
Kang SM, et al.
Advances in Functional Materials, 21(1), 108-112 (2011)
Yuki Komoto et al.
Scientific reports, 10(1), 11244-11244 (2020-07-11)
The analysis of neurotransmitters in the brain helps to understand brain functions and diagnose Parkinson's disease. Pharmacological inhibition experiments, electrophysiological measurement of action potentials, and mass analysers have been applied for this purpose; however, these techniques do not allow direct
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