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Merck
CN

A55500

2-Aminofluorene

98%

Synonym(s):

2-Fluorenamine, 2-Fluorenylamine

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About This Item

Empirical Formula (Hill Notation):
C13H11N
CAS Number:
Molecular Weight:
181.23
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
205-817-8
Beilstein/REAXYS Number:
1945861
MDL number:
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Product Name

2-Aminofluorene, 98%

InChI key

CFRFHWQYWJMEJN-UHFFFAOYSA-N

InChI

1S/C13H11N/c14-11-5-6-13-10(8-11)7-9-3-1-2-4-12(9)13/h1-6,8H,7,14H2

SMILES string

Nc1ccc-2c(Cc3ccccc-23)c1

assay

98%

form

powder

mp

124-128 °C (lit.)

Quality Level

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pictograms

Health hazardEnvironment

signalword

Warning

hcodes

Hazard Classifications

Aquatic Chronic 2 - Carc. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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R H Heflich et al.
Mutation research, 318(2), 73-114 (1994-10-01)
2-Acetylaminofluorene and 2-aminofluorene are among the most intensively studied of all chemical mutagens and carcinogens. Fundamental research findings concerning the metabolism of 2-acetylaminofluorene to electrophilic derivatives, the interaction of these derivatives with DNA, and the carcinogenic and mutagenic responses that
Nidhi Jain et al.
Chemical research in toxicology, 21(2), 445-452 (2008-01-16)
Fluorescence spectroscopy was used to study carcinogen-induced conformational heterogeneity in DNA duplexes. The fluorophore 2-aminopurine (AP) was incorporated adjacent (5') to the lesion (G*) in eight different DNA duplexes [d(5'-CTTCT PG* NCCTC-3'):d(5'-GAGGN XTAGAAG-3'), G* = FAF adduct, P = AP
Ali Bilici et al.
Biomacromolecules, 11(10), 2593-2601 (2010-09-08)
In this paper, the results on horseradish peroxidase (HRP)-catalyzed oxidative polymerization of amine-functionalized fluorene monomer, 2-amino fluorene (AF), are reported. The resulting polymer exhibits an exciting molecular structure and spectral properties. FT-IR and NMR studies show that the two fluorene
Jun Zhao et al.
Stem cell research & therapy, 10(1), 165-165 (2019-06-15)
Mounting evidence has shown that a novel subset of mesenchymal stem cells (MSCs) derived from human gingiva referred to as gingival mesenchymal stem cells (GMSCs) displays a greater immunotherapeutic potential and regenerative repair expression than MSCs obtained from other tissues.
Olga Rechkoblit et al.
Nature structural & molecular biology, 17(3), 379-388 (2010-02-16)
The aromatic amine carcinogen 2-aminofluorene (AF) forms covalent adducts with DNA, predominantly with guanine at the C8 position. Such lesions are bypassed by Y-family polymerases such as Dpo4 via error-free and error-prone mechanisms. We show that Dpo4 catalyzes elongation from

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